Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid

World J Gastroenterol. 2015 Oct 7;21(37):10704-8. doi: 10.3748/wjg.v21.i37.10704.

Abstract

Addiction to synthetic cannabinoids (SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation (AGD) and hepatic portal venous gas (HPVG), with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic follow-up was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG, which can be managed non-surgically despite the findings of acute abdomen.

Keywords: Acute abdomen; Acute gastric dilatation; Bonzai; Hepatic portal venous gas; Synthetic cannabinoid.

Publication types

  • Case Reports

MeSH terms

  • Abdomen, Acute / etiology
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Blood Gas Analysis
  • Cannabinoids / adverse effects*
  • Embolism, Air / etiology*
  • Endoscopy
  • Gases
  • Gastric Dilatation / chemically induced*
  • Gastric Mucosa / pathology
  • Humans
  • Ischemia / pathology
  • Liver / diagnostic imaging*
  • Liver / drug effects
  • Male
  • Portal Vein / diagnostic imaging*
  • Radiography, Abdominal
  • Substance-Related Disorders*
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents
  • Cannabinoids
  • Gases