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Ribosomal leaky scanning through a translated uORF requires eIF4G2.
Smirnova VV, Shestakova ED, Nogina DS, Mishchenko PA, Prikazchikova TA, Zatsepin TS, Kulakovskiy IV, Shatsky IN, Terenin IM. Smirnova VV, et al. Among authors: shestakova ed. Nucleic Acids Res. 2022 Jan 25;50(2):1111-1127. doi: 10.1093/nar/gkab1286. Nucleic Acids Res. 2022. PMID: 35018467 Free PMC article.
eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop.
Smirnova VV, Shestakova ED, Bikmetov DV, Chugunova AA, Osterman IA, Serebryakova MV, Sergeeva OV, Zatsepin TS, Shatsky IN, Terenin IM. Smirnova VV, et al. Among authors: shestakova ed. RNA. 2019 Jul;25(7):757-767. doi: 10.1261/rna.065623.118. Epub 2019 Apr 22. RNA. 2019. PMID: 31010886 Free PMC article.