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The following term was not found in PubMed: ongwongsakul
Page 1
Showing results for ecarin ongwongsakul
Search for Ekarin Ongwongsakul instead (1 results)
Ecarin based coagulation testing.
Gosselin RC, Douxfils J. Gosselin RC, et al. Am J Hematol. 2020 Jul;95(7):863-869. doi: 10.1002/ajh.25852. Epub 2020 May 30. Am J Hematol. 2020. PMID: 32350907 Free article. Review.
Ecarin is derived from venom of Echis carinatus, and will activate prothrombin into meizothrombin which will then cleave fibrinogen to result in clot formation. Ecarin based testing has been described for decades, but these assays were typically restricted to refere …
Ecarin is derived from venom of Echis carinatus, and will activate prothrombin into meizothrombin which will then cleave fibrinogen t …
Testing for Lupus Anticoagulants.
Moore GW. Moore GW. Semin Thromb Hemost. 2022 Sep;48(6):643-660. doi: 10.1055/s-0042-1744363. Epub 2022 Jun 1. Semin Thromb Hemost. 2022. PMID: 35649428 Review.
Nonetheless, judicious use of other assays can improve diagnostic performance, such as dilute prothrombin time to find LA unreactive with dRVVT and aPTT, and the recently validated Taipan snake venom time with ecarin time confirmatory test that are unaffected by vitamin K …
Nonetheless, judicious use of other assays can improve diagnostic performance, such as dilute prothrombin time to find LA unreactive with dR …
Ecarin-Based Methods for Measuring Thrombin Inhibitors.
Gosselin RC. Gosselin RC. Methods Mol Biol. 2023;2663:355-367. doi: 10.1007/978-1-0716-3175-1_23. Methods Mol Biol. 2023. PMID: 37204723
Ecarin is a venom from the saw-scaled viper, Echis carinatus, which catalyzes prothrombin into meizothrombin. This venom is used in several hemostasis laboratory assays, including ecarin clotting time (ECT) and ecarin chromogenic assays (ECA). The use of thes …
Ecarin is a venom from the saw-scaled viper, Echis carinatus, which catalyzes prothrombin into meizothrombin. This venom is used in s …
Idarucizumab for Dabigatran Reversal - Full Cohort Analysis.
Pollack CV Jr, Reilly PA, van Ryn J, Eikelboom JW, Glund S, Bernstein RA, Dubiel R, Huisman MV, Hylek EM, Kam CW, Kamphuisen PW, Kreuzer J, Levy JH, Royle G, Sellke FW, Stangier J, Steiner T, Verhamme P, Wang B, Young L, Weitz JI. Pollack CV Jr, et al. N Engl J Med. 2017 Aug 3;377(5):431-441. doi: 10.1056/NEJMoa1707278. Epub 2017 Jul 11. N Engl J Med. 2017. PMID: 28693366 Free article. Clinical Trial.
The primary end point was the maximum percentage reversal of the anticoagulant effect of dabigatran within 4 hours after the administration of idarucizumab, on the basis of the diluted thrombin time or ecarin clotting time. Secondary end points included the restoration of …
The primary end point was the maximum percentage reversal of the anticoagulant effect of dabigatran within 4 hours after the administration …
Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants: A Systematic Review.
Samuelson BT, Cuker A, Siegal DM, Crowther M, Garcia DA. Samuelson BT, et al. Chest. 2017 Jan;151(1):127-138. doi: 10.1016/j.chest.2016.08.1462. Epub 2016 Sep 13. Chest. 2017. PMID: 27637548 Free PMC article. Review.
Dilute thrombin time (TT) assays demonstrated linear correlation (r(2) = 0.67-0.99) across a range of expected concentrations of dabigatran, as did ecarin-based assays. Calibrated anti-Xa assays demonstrated linear correlation (r(2) = 0.78-1.00) across a wide range of conc …
Dilute thrombin time (TT) assays demonstrated linear correlation (r(2) = 0.67-0.99) across a range of expected concentrations of dabigatran, …
Potential Application of Recombinant Snake Prothrombin Activator Ecarin in Blood Diagnostics.
Zhao KN, Masci P, Dimeski G, Johnson L, Grant M, de Jersey J, Lavin MF. Zhao KN, et al. Biomolecules. 2022 Nov 17;12(11):1704. doi: 10.3390/biom12111704. Biomolecules. 2022. PMID: 36421717 Free PMC article.
Expression of recombinant ecarin (rEcarin) was carried out in human embryonic kidney cells (HEK) cells under conditions for the development and performance of a novel and scalable recombinant snake ecarin to industry standards. Clotting performance of the rEcarin wa …
Expression of recombinant ecarin (rEcarin) was carried out in human embryonic kidney cells (HEK) cells under conditions for the devel …
Expression and characterization of recombinant ecarin.
Jonebring A, Lange U, Bucha E, Deinum J, Elg M, Lövgren A. Jonebring A, et al. Protein J. 2012 Jun;31(5):353-8. doi: 10.1007/s10930-012-9409-6. Protein J. 2012. PMID: 22528138 Free PMC article.
At low concentrations both these proteins were converted into thrombin by the two ecarin preparations with comparable rates. However, with prothrombin concentrations above 250 nM r-ecarin apparently had a two times higher turnover than native ecarin, consiste …
At low concentrations both these proteins were converted into thrombin by the two ecarin preparations with comparable rates. However, …
Congenital prothrombin deficiency.
Lancellotti S, De Cristofaro R. Lancellotti S, et al. Semin Thromb Hemost. 2009 Jun;35(4):367-81. doi: 10.1055/s-0029-1225759. Epub 2009 Jul 13. Semin Thromb Hemost. 2009. PMID: 19598065 Review.
The ecarin clotting time, a universal method to quantify direct thrombin inhibitors.
Nowak G. Nowak G. Pathophysiol Haemost Thromb. 2003 Jul-2004 Aug;33(4):173-83. doi: 10.1159/000081505. Pathophysiol Haemost Thromb. 2003. PMID: 15583446 Free article. Review.
The ecarin clotting time (ECT) is a meizothrombin generation test that allows for precise quantification of direct thrombin inhibitors. ...
The ecarin clotting time (ECT) is a meizothrombin generation test that allows for precise quantification of direct thrombin inhibitor …
368 results