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QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene.
Org Biomol Chem. 2023 Dec 20;22(1):55-58. doi: 10.1039/d3ob01464a.
Org Biomol Chem. 2023.
PMID: 37970888
Free PMC article.
The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer.
Ahmed AA, Greenhalf W, Palmer DH, Williams N, Worthington J, Arshad T, Haider S, Alexandrou E, Guneri D, Waller ZAE, Neidle S.
Ahmed AA, et al. Among authors: alexandrou e.
Molecules. 2023 Mar 7;28(6):2452. doi: 10.3390/molecules28062452.
Molecules. 2023.
PMID: 36985425
Free PMC article.
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