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Candidalysin Is the Hemolytic Factor of Candida albicans.
Mogavero S, Höfs S, Lauer AN, Müller R, Brunke S, Allert S, Gerwien F, Groth S, Dolk E, Wilson D, Gutsmann T, Hube B. Mogavero S, et al. Among authors: dolk e. Toxins (Basel). 2022 Dec 15;14(12):874. doi: 10.3390/toxins14120874. Toxins (Basel). 2022. PMID: 36548771 Free PMC article.
Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies.
Struijf EM, De la O Becerra KI, Ruyken M, de Haas CJC, van Oosterom F, Siere DY, van Keulen JE, Heesterbeek DAC, Dolk E, Heukers R, Bardoel BW, Gros P, Rooijakkers SHM. Struijf EM, et al. Among authors: dolk e. J Biol Chem. 2023 Aug;299(8):104956. doi: 10.1016/j.jbc.2023.104956. Epub 2023 Jun 23. J Biol Chem. 2023. PMID: 37356719 Free PMC article.
Selection of VHHs under application conditions.
Dolk E, Verrips T, de Haard H. Dolk E, et al. Methods Mol Biol. 2012;911:199-209. doi: 10.1007/978-1-61779-968-6_13. Methods Mol Biol. 2012. PMID: 22886254
Enhancement of polymeric immunoglobulin receptor transcytosis by biparatopic VHH.
Emmerson CD, van der Vlist EJ, Braam MR, Vanlandschoot P, Merchiers P, de Haard HJ, Verrips CT, van Bergen en Henegouwen PM, Dolk E. Emmerson CD, et al. Among authors: dolk e. PLoS One. 2011;6(10):e26299. doi: 10.1371/journal.pone.0026299. Epub 2011 Oct 14. PLoS One. 2011. PMID: 22022593 Free PMC article.
Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis.
Valentine M, Rudolph P, Dietschmann A, Tsavou A, Mogavero S, Lee S, Priest EL, Zhurgenbayeva G, Jablonowski N, Timme S, Eggeling C, Allert S, Dolk E, Naglik JR, Figge MT, Gresnigt MS, Hube B. Valentine M, et al. Among authors: dolk e. mBio. 2024 Mar 13;15(3):e0340923. doi: 10.1128/mbio.03409-23. Epub 2024 Feb 13. mBio. 2024. PMID: 38349176 Free PMC article.
13 results