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3D chromatin remodeling potentiates transcriptional programs driving cell invasion.
Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2203452119. doi: 10.1073/pnas.2203452119. Epub 2022 Aug 29.
Proc Natl Acad Sci U S A. 2022.
PMID: 36037342
Free PMC article.
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.
Totten SP, Im YK, Cepeda Cañedo E, Najyb O, Nguyen A, Hébert S, Ahn R, Lewis K, Lebeau B, La Selva R, Sabourin V, Martínez C, Savage P, Kuasne H, Avizonis D, Santos Martínez N, Chabot C, Aguilar-Mahecha A, Goulet ML, Dankner M, Witcher M, Petrecca K, Basik M, Pollak M, Topisirovic I, Lin R, Siegel PM, Kleinman CL, Park M, St-Pierre J, Ursini-Siegel J.
Totten SP, et al. Among authors: cepeda canedo e.
Nat Commun. 2021 Jun 3;12(1):3299. doi: 10.1038/s41467-021-23396-2.
Nat Commun. 2021.
PMID: 34083537
Free PMC article.
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p66ShcA potentiates the cytotoxic response of triple-negative breast cancers to PARP inhibitors.
Cañedo EC, Totten S, Ahn R, Savage P, MacNeil D, Hudson J, Autexier C, Deblois G, Park M, Witcher M, Ursini-Siegel J.
Cañedo EC, et al.
JCI Insight. 2021 Feb 22;6(4):e138382. doi: 10.1172/jci.insight.138382.
JCI Insight. 2021.
PMID: 33470989
Free PMC article.
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p66ShcA functions as a contextual promoter of breast cancer metastasis.
Lewis K, Kiepas A, Hudson J, Senecal J, Ha JR, Voorand E, Annis MG, Sabourin V, Ahn R, La Selva R, Tabariès S, Hsu BE, Siegel MJ, Dankner M, Canedo EC, Lajoie M, Watson IR, Brown CM, Siegel PM, Ursini-Siegel J.
Lewis K, et al. Among authors: canedo ec.
Breast Cancer Res. 2020 Jan 15;22(1):7. doi: 10.1186/s13058-020-1245-6.
Breast Cancer Res. 2020.
PMID: 31941526
Free PMC article.
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p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress.
Lewis K, La Selva R, Maldonado E, Annis MG, Najyb O, Cepeda Cañedo E, Totten S, Hébert S, Sabourin V, Mirabelli C, Ciccolini E, Lehuédé C, Choinière L, Russo M, Avizonis D, Park M, St-Pierre J, Kleinman CL, Siegel PM, Ursini-Siegel J.
Lewis K, et al. Among authors: cepeda canedo e.
Redox Biol. 2024 Apr;70:103028. doi: 10.1016/j.redox.2024.103028. Epub 2024 Jan 5.
Redox Biol. 2024.
PMID: 38211442
Free PMC article.
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Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance.
Ha JR, Ahn R, Smith HW, Sabourin V, Hébert S, Cepeda Cañedo E, Im YK, Kleinman CL, Muller WJ, Ursini-Siegel J.
Ha JR, et al. Among authors: cepeda canedo e.
Mol Cancer Res. 2018 May;16(5):894-908. doi: 10.1158/1541-7786.MCR-17-0623. Epub 2018 Feb 16.
Mol Cancer Res. 2018.
PMID: 29453318
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Bioaccessibility, Intestinal Permeability and Plasma Stability of Isorhamnetin Glycosides from Opuntia ficus-indica (L.).
Antunes-Ricardo M, Rodríguez-Rodríguez C, Gutiérrez-Uribe JA, Cepeda-Cañedo E, Serna-Saldívar SO.
Antunes-Ricardo M, et al. Among authors: cepeda canedo e.
Int J Mol Sci. 2017 Aug 22;18(8):1816. doi: 10.3390/ijms18081816.
Int J Mol Sci. 2017.
PMID: 28829356
Free PMC article.
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