Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2003 1
2008 1
2010 2
2011 1
2015 3
2016 4
2017 3
2018 7
2019 4
2021 6
2022 2
2023 5
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

34 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for edited kaufman
Your search for Edīte Kaufmane retrieved no results
Design and testing of a humanized porcine donor for xenotransplantation.
Anand RP, Layer JV, Heja D, Hirose T, Lassiter G, Firl DJ, Paragas VB, Akkad A, Chhangawala S, Colvin RB, Ernst RJ, Esch N, Getchell K, Griffin AK, Guo X, Hall KC, Hamilton P, Kalekar LA, Kan Y, Karadagi A, Li F, Low SC, Matheson R, Nehring C, Otsuka R, Pandelakis M, Policastro RA, Pols R, Queiroz L, Rosales IA, Serkin WT, Stiede K, Tomosugi T, Xue Y, Zentner GE, Angeles-Albores D, Chris Chao J, Crabtree JN, Harken S, Hinkle N, Lemos T, Li M, Pantano L, Stevens D, Subedar OD, Tan X, Yin S, Anwar IJ, Aufhauser D, Capuano S, Kaufman DB, Knechtle SJ, Kwun J, Shanmuganayagam D, Markmann JF, Church GM, Curtis M, Kawai T, Youd ME, Qin W. Anand RP, et al. Nature. 2023 Oct;622(7982):393-401. doi: 10.1038/s41586-023-06594-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821590 Free PMC article.
Here we describe the design, creation and long-term life-supporting function of kidney grafts from a genetically engineered porcine donor transplanted into a cynomolgus monkey model. The porcine donor was engineered to carry 69 genomic edits, eliminating glycan antigens, o …
Here we describe the design, creation and long-term life-supporting function of kidney grafts from a genetically engineered porcine donor tr …
Induced pluripotent stem cell-derived engineered T cells, natural killer cells, macrophages, and dendritic cells in immunotherapy.
Xue D, Lu S, Zhang H, Zhang L, Dai Z, Kaufman DS, Zhang J. Xue D, et al. Trends Biotechnol. 2023 Jul;41(7):907-922. doi: 10.1016/j.tibtech.2023.02.003. Epub 2023 Feb 28. Trends Biotechnol. 2023. PMID: 36858941 Review.
This review outlines the utility of four iPSC-derived immune-cell-based therapies, highlight the latest progress and future trends in the genome-editing strategies designed to improve efficacy, safety, and universality, and provides perspectives that compare different cont …
This review outlines the utility of four iPSC-derived immune-cell-based therapies, highlight the latest progress and future trends in the ge …
Management of Salivary Gland Malignancy: ASCO Guideline.
Geiger JL, Ismaila N, Beadle B, Caudell JJ, Chau N, Deschler D, Glastonbury C, Kaufman M, Lamarre E, Lau HY, Licitra L, Moore MG, Rodriguez C, Roshal A, Seethala R, Swiecicki P, Ha P. Geiger JL, et al. J Clin Oncol. 2021 Jun 10;39(17):1909-1941. doi: 10.1200/JCO.21.00449. Epub 2021 Apr 26. J Clin Oncol. 2021. PMID: 33900808
Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis.
Doke T, Huang S, Qiu C, Liu H, Guan Y, Hu H, Ma Z, Wu J, Miao Z, Sheng X, Zhou J, Cao A, Li J, Kaufman L, Hung A, Brown CD, Pestell R, Susztak K. Doke T, et al. J Clin Invest. 2021 May 17;131(10):e141801. doi: 10.1172/JCI141801. J Clin Invest. 2021. PMID: 33998598 Free PMC article.
Human and mouse kidney single-cell open chromatin data (snATAC-Seq) prioritized estimated glomerular filtration rate (eGFR) GWAS variants located on an intronic regulatory region in distal convoluted tubule cells. CRISPR-Cas9-mediated gene editing confirmed the role of ris …
Human and mouse kidney single-cell open chromatin data (snATAC-Seq) prioritized estimated glomerular filtration rate (eGFR) GWAS variants lo …
Genome-wide Association Study for AKI.
Bhatraju PK, Stanaway IB, Palmer MR, Menon R, Schaub JA, Menez S, Srivastava A, Wilson FP, Kiryluk K, Palevsky PM, Naik AS, Sakr SS, Jarvik GP, Parikh CR, Ware LB, Ikizler TA, Siew ED, Chinchilli VM, Coca SG, Garg AX, Go AS, Kaufman JS, Kimmel PL, Himmelfarb J, Wurfel MM. Bhatraju PK, et al. Kidney360. 2023 Jul 1;4(7):870-880. doi: 10.34067/KID.0000000000000175. Epub 2023 Jun 5. Kidney360. 2023. PMID: 37273234 Free PMC article.
What Surgeons Need to Know About Gene Therapy for Cancer.
Sivarajah S, Emerick K, Kaufman HL. Sivarajah S, et al. Adv Surg. 2022 Sep;56(1):151-168. doi: 10.1016/j.yasu.2022.02.006. Adv Surg. 2022. PMID: 36096566 Review.
An understanding of the different modalities including gene replacement therapy, cancer vaccines, oncolytic viruses, cellular therapy, and gene editing is essential for managing patients with neoplastic disease. ...
An understanding of the different modalities including gene replacement therapy, cancer vaccines, oncolytic viruses, cellular therapy, and g …
Into the multiverse of gene edited NK cell-based therapeutic strategies.
Goldenson BH, Kaufman DS. Goldenson BH, et al. Cell Stem Cell. 2021 Dec 2;28(12):2041-2043. doi: 10.1016/j.stem.2021.11.004. Cell Stem Cell. 2021. PMID: 34861144 Free article.
., (2021) investigate the anti-cancer activity of triple gene edited iPSC-derived natural killer (NK) cells and demonstrate that expression of a modified CD16a and interleukin (IL)-15 receptor combined with knockout of CD38 improves NK cell-mediated activity against leukem …
., (2021) investigate the anti-cancer activity of triple gene edited iPSC-derived natural killer (NK) cells and demonstrate that expr …
Pluripotent stem cell applications for regenerative medicine.
Angelos MG, Kaufman DS. Angelos MG, et al. Curr Opin Organ Transplant. 2015 Dec;20(6):663-70. doi: 10.1097/MOT.0000000000000244. Curr Opin Organ Transplant. 2015. PMID: 26536430 Free PMC article. Review.
Advances using the clustered regulatory interspaced short palindromic repeats (CRISPR)/Cas9 gene-editing system offer an improved tool for more rapid and on-target gene correction of genetic diseases. ...
Advances using the clustered regulatory interspaced short palindromic repeats (CRISPR)/Cas9 gene-editing system offer an improved too …
Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells.
Saetersmoen ML, Hammer Q, Valamehr B, Kaufman DS, Malmberg KJ. Saetersmoen ML, et al. Semin Immunopathol. 2019 Jan;41(1):59-68. doi: 10.1007/s00281-018-0721-x. Epub 2018 Oct 25. Semin Immunopathol. 2019. PMID: 30361801 Review.
Currently, FDA-approved CAR-T cell products are based on engineering of autologous T cells harvested from the patient, typically using a central manufacturing facility for gene editing before the product can be delivered to the clinic and infused to the patients. ...
Currently, FDA-approved CAR-T cell products are based on engineering of autologous T cells harvested from the patient, typically using a cen …
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.
Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, Kaufman HL, Kirchhoff T, Lotze MT, Luke JJ, Minn AJ, Politi K, Shultz LD, Simon R, Thórsson V, Weidhaas JB, Ascierto ML, Ascierto PA, Barnes JM, Barsan V, Bommareddy PK, Bot A, Church SE, Ciliberto G, De Maria A, Draganov D, Ho WS, McGee HM, Monette A, Murphy JF, Nisticò P, Park W, Patel M, Quigley M, Radvanyi L, Raftopoulos H, Rudqvist NP, Snyder A, Sweis RF, Valpione S, Zappasodi R, Butterfield LH, Disis ML, Fox BA, Cesano A, Marincola FM; Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups. Bedognetti D, et al. J Immunother Cancer. 2019 May 22;7(1):131. doi: 10.1186/s40425-019-0602-4. J Immunother Cancer. 2019. PMID: 31113486 Free PMC article. Review.
The multifactorial determinants of CIR include the genetic makeup of the patient, the genomic instability central to cancer development, the evolutionary emergence of cancer phenotypes under the influence of immune editing, and external modifiers such as demographics, envi …
The multifactorial determinants of CIR include the genetic makeup of the patient, the genomic instability central to cancer development, the …
34 results