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2000 1
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Page 1
Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer.
Tutt ANJ, Garber JE, Kaufman B, Viale G, Fumagalli D, Rastogi P, Gelber RD, de Azambuja E, Fielding A, Balmaña J, Domchek SM, Gelmon KA, Hollingsworth SJ, Korde LA, Linderholm B, Bandos H, Senkus E, Suga JM, Shao Z, Pippas AW, Nowecki Z, Huzarski T, Ganz PA, Lucas PC, Baker N, Loibl S, McConnell R, Piccart M, Schmutzler R, Steger GG, Costantino JP, Arahmani A, Wolmark N, McFadden E, Karantza V, Lakhani SR, Yothers G, Campbell C, Geyer CE Jr; OlympiA Clinical Trial Steering Committee and Investigators. Tutt ANJ, et al. N Engl J Med. 2021 Jun 24;384(25):2394-2405. doi: 10.1056/NEJMoa2105215. Epub 2021 Jun 3. N Engl J Med. 2021. PMID: 34081848 Free PMC article. Clinical Trial.
E-Cigarette Flavoring Chemicals Induce Cytotoxicity in HepG2 Cells.
Rickard BP, Ho H, Tiley JB, Jaspers I, Brouwer KLR. Rickard BP, et al. ACS Omega. 2021 Mar 2;6(10):6708-6713. doi: 10.1021/acsomega.0c05639. eCollection 2021 Mar 16. ACS Omega. 2021. PMID: 33748584 Free PMC article.
E-cigarette-related hospitalizations and deaths across the U.S. continue to increase. A high percentage of patients have elevated liver function tests indicative of systemic toxicity. This study was designed to determine the effect of e-cigarette chemicals on liver …
E-cigarette-related hospitalizations and deaths across the U.S. continue to increase. A high percentage of patients have elevated liv …
Estimation of species divergence times in presence of cross-species gene flow.
Tiley GP, Flouri T, Jiao X, Poelstra JW, Xu B, Zhu T, Rannala B, Yoder AD, Yang Z. Tiley GP, et al. Syst Biol. 2023 Aug 7;72(4):820-836. doi: 10.1093/sysbio/syad015. Syst Biol. 2023. PMID: 36961245 Free PMC article.
We characterize some general expectations for biases in divergence time estimation under three different scenarios: 1) introgression between sister species, 2) introgression between non-sister species, and 3) introgression from an unsampled (i.e., ghost) outgroup lineage. …
We characterize some general expectations for biases in divergence time estimation under three different scenarios: 1) introgression between …
'Real-world' Australian experience of pomalidomide for relapsed and refractory myeloma.
Scott A, Weber N, Tiley C, Taylor K, Taper J, Harrison S, Chan KL, Stark R, Lee C, Morris K, Ho PJ, Dodds A, Ramanathan S, Ramakrishna R, Watson AM, Auguston B, Kwok F, Quach H, Warburton P, Rowlings P, Mollee P. Scott A, et al. Leuk Lymphoma. 2018 Jun;59(6):1514-1516. doi: 10.1080/10428194.2017.1387911. Epub 2017 Oct 12. Leuk Lymphoma. 2018. PMID: 29022836 No abstract available.
Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur.
Campbell CR, Tiley GP, Poelstra JW, Hunnicutt KE, Larsen PA, Lee HJ, Thorne JL, Dos Reis M, Yoder AD. Campbell CR, et al. Heredity (Edinb). 2021 Aug;127(2):233-244. doi: 10.1038/s41437-021-00446-5. Epub 2021 Jul 16. Heredity (Edinb). 2021. PMID: 34272504 Free PMC article.
Our study provides the first direct mutation-rate estimate for a strepsirrhine (i.e., the lemurs and lorises), which comprises nearly half of the primate clade. ...
Our study provides the first direct mutation-rate estimate for a strepsirrhine (i.e., the lemurs and lorises), which comprises nearly …
Evolution of l-DOPA 4,5-dioxygenase activity allows for recurrent specialisation to betalain pigmentation in Caryophyllales.
Sheehan H, Feng T, Walker-Hale N, Lopez-Nieves S, Pucker B, Guo R, Yim WC, Badgami R, Timoneda A, Zhao L, Tiley H, Copetti D, Sanderson MJ, Cushman JC, Moore MJ, Smith SA, Brockington SF. Sheehan H, et al. New Phytol. 2020 Aug;227(3):914-929. doi: 10.1111/nph.16089. Epub 2019 Sep 29. New Phytol. 2020. PMID: 31369159 Free PMC article.
Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals.
Hunnicutt KE, Tiley GP, Williams RC, Larsen PA, Blanco MB, Rasoloarison RM, Campbell CR, Zhu K, Weisrock DW, Matsunami H, Yoder AD. Hunnicutt KE, et al. Genome Biol Evol. 2020 Jan 1;12(1):3562-3579. doi: 10.1093/gbe/evz200. Genome Biol Evol. 2020. PMID: 31555816 Free PMC article.
By doubling the existing genomic resources for strepsirrhine primates (i.e. the lemurs and lorises), we find that the highly speciose and morphologically cryptic mouse lemurs have experienced an elaborate proliferation of V1Rs that we argue is functionally related to their …
By doubling the existing genomic resources for strepsirrhine primates (i.e. the lemurs and lorises), we find that the highly speciose …
Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.
Hussein IT, Miguel RN, Tiley LS, Field HJ. Hussein IT, et al. Arch Virol. 2008;153(3):495-505. doi: 10.1007/s00705-007-0021-6. Epub 2008 Jan 15. Arch Virol. 2008. PMID: 18196203
The virus-encoded thymidine kinase (TK) is the molecular basis for selective activation of commonly used antiviral nucleoside analogue drugs, e.g. acyclovir (ACV), penciclovir (PCV) and ganciclovir (GCV). ...
The virus-encoded thymidine kinase (TK) is the molecular basis for selective activation of commonly used antiviral nucleoside analogue drugs …
14 results