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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2004 1
2006 1
2013 1
2014 3
2015 2
2016 5
2017 1
2018 2
2019 1
2020 3
2021 2
2022 5
2023 2
2024 0

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28 results

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Page 1
A vitamin E long-chain metabolite and the inspired drug candidate alpha-amplexichromanol relieve asthma features in an experimental model of allergen sensitization.
Cerqua I, Neukirch K, Terlizzi M, Granato E, Caiazzo E, Cicala C, Ialenti A, Capasso R, Werz O, Sorrentino R, Seraphin D, Helesbeux JJ, Cirino G, Koeberle A, Roviezzo F, Rossi A. Cerqua I, et al. Pharmacol Res. 2022 Jul;181:106250. doi: 10.1016/j.phrs.2022.106250. Epub 2022 May 10. Pharmacol Res. 2022. PMID: 35562015
Benefits for vitamin E intake in diseases with inflammatory components have been described and related in part, to endogenously formed metabolites (long-chain metabolites, LCM). ...In conclusion, this study highlights a role for LCM and of vitamin E derivatives as p …
Benefits for vitamin E intake in diseases with inflammatory components have been described and related in part, to endogenously forme …
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.
Systemic vitamin E metabolites have been proposed as signaling molecules, but their physiological role is unknown. Here we show, by library screening of potential human vitamin E metabolites, that long-chain omega-carboxylates are potent allosteric inhibitors of 5-l …
Systemic vitamin E metabolites have been proposed as signaling molecules, but their physiological role is unknown. Here we show, by l …
A mobile battery-powered brain perfusion ultrasound (BPU) device designed for prehospital stroke diagnosis: correlation to perfusion MRI in healthy volunteers.
Kilic M, Scalzo F, Lyle C, Baldaranov D, Dirnbacher M, Honda T, Liebeskind DS, Schlachetzki F. Kilic M, et al. Neurol Res Pract. 2022 Apr 11;4(1):13. doi: 10.1186/s42466-022-00179-8. Neurol Res Pract. 2022. PMID: 35399083 Free PMC article.
We report on a novel small, portable and battery driven point-of-care ultrasound system (SONAS) specifically developed for mobile non-invasive brain perfusion ultrasound (BPU) measurement after bolus injection of an echo-enhancing agent suitable for the use in prehospital …
We report on a novel small, portable and battery driven point-of-care ultrasound system (SONAS) specifically developed for mobile non …
Acute Middle Cerebral Artery Occlusion Detection Using Mobile Non-Imaging Brain Perfusion Ultrasound-First Case.
Kilic M, Wendl C, Wilfling S, Olmes D, Linker RA, Schlachetzki F. Kilic M, et al. J Clin Med. 2022 Jun 13;11(12):3384. doi: 10.3390/jcm11123384. J Clin Med. 2022. PMID: 35743454 Free PMC article.
Mobile brain perfusion ultrasound (BPU) is a novel non-imaging technique creating only hemispheric perfusion curves following ultrasound contrast injection and has been specifically designed for early prehospital large vessel occlusion (LVO) stroke identification. We report on th …
Mobile brain perfusion ultrasound (BPU) is a novel non-imaging technique creating only hemispheric perfusion curves following ultrasound con …
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation.
Neukirch K, Alsabil K, Dinh CP, Bilancia R, Raasch M, Ville A, Cerqua I, Viault G, Bréard D, Pace S, Temml V, Brunner E, Jordan PM, Marques MC, Loeser K, Gollowitzer A, Permann S, Gerstmeier J, Lorkowski S, Stuppner H, Garscha U, Rodrigues T, Bernardes GJL, Schuster D, Séraphin D, Richomme P, Rossi A, Mosig AS, Roviezzo F, Werz O, Helesbeux JJ, Koeberle A. Neukirch K, et al. J Med Chem. 2021 Aug 12;64(15):11496-11526. doi: 10.1021/acs.jmedchem.1c00806. Epub 2021 Jul 19. J Med Chem. 2021. PMID: 34279935 Free PMC article.
Endogenous long-chain metabolites of vitamin E (LCMs) mediate immune functions by targeting 5-lipoxygenase (5-LOX) and increasing the systemic concentrations of resolvin E3, a specialized proresolving lipid mediator. ...Other enzymes within lipid mediator biosynthesis were …
Endogenous long-chain metabolites of vitamin E (LCMs) mediate immune functions by targeting 5-lipoxygenase (5-LOX) and increasing the …
Cognitive indicators of social anxiety in youth: a structural equation analysis.
Rudy BM, Davis TE 3rd, Matthews RA. Rudy BM, et al. Behav Ther. 2014 Jan;45(1):116-25. doi: 10.1016/j.beth.2013.09.003. Epub 2013 Sep 21. Behav Ther. 2014. PMID: 24411119
Therefore, the purpose of the present study was to examine domain-specific cognitive variables (i.e., socially oriented negative self-referent cognition and social self-efficacy) and their relationships to social anxiety in children and adolescents using structural equatio …
Therefore, the purpose of the present study was to examine domain-specific cognitive variables (i.e., socially oriented negative self …
Stress response dampening indexed by cortisol in subjects at risk for alcoholism.
Croissant B, Olbrich R. Croissant B, et al. J Stud Alcohol. 2004 Nov;65(6):701-7. doi: 10.15288/jsa.2004.65.701. J Stud Alcohol. 2004. PMID: 15700506
In our report we address the question of whether people with a family history of alcoholism exhibit dampening effects of ethanol in the response of a classical stress hormone (i.e., cortisol). METHOD: Subjects in this report were 46 healthy male and 40 healthy female adult …
In our report we address the question of whether people with a family history of alcoholism exhibit dampening effects of ethanol in the resp …
13C NMR-based dereplication using MixONat software to decipher potent anti-cholinesterase compounds in Mesua lepidota bark.
Leong ST, Liew SY, Khaw KY, Ahmad Hassali H, Richomme P, Derbré S, Lee VS, Yahya R, Awang K. Leong ST, et al. Bioorg Chem. 2023 Dec;141:106859. doi: 10.1016/j.bioorg.2023.106859. Epub 2023 Sep 11. Bioorg Chem. 2023. PMID: 37742494
Eight compounds were identified with the aid of the (13)C NMR-based dereplication software, MixONat, i.e., sitosterol (1), stigmasterol (2), alpha-amyrin (3), friedelin (6), 3beta-friedelinol (7), betulinic acid (9), lepidotol A (10) and lepidotol B (11). Further bio-assay …
Eight compounds were identified with the aid of the (13)C NMR-based dereplication software, MixONat, i.e., sitosterol (1), stigmaster …
28 results