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Ascites in ovarian cancer: MicroRNA deregulations and their potential roles in ovarian carcinogenesis.
Záveský L, Jandáková E, Weinberger V, Hanzíková V, Slanař O, Kohoutová M. Záveský L, et al. Cancer Biomark. 2022;33(1):1-16. doi: 10.3233/CBM-210219. Cancer Biomark. 2022. PMID: 34511487 Review.
The article focuses on a number of miRNAs that share a common expression pattern as determined by independent studies using ascites samples and with regard to their functions and outcomes in experimental and clinical investigations.Let-7b and miR-143 have featured as tumor suppre …
The article focuses on a number of miRNAs that share a common expression pattern as determined by independent studies using ascites samples …
WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer.
Kotrbová A, Ovesná P, Gybel' T, Radaszkiewicz T, Bednaříková M, Hausnerová J, Jandáková E, Minář L, Crha I, Weinberger V, Záveský L, Bryja V, Pospíchalová V. Kotrbová A, et al. Theranostics. 2020 Jan 1;10(2):537-552. doi: 10.7150/thno.37423. eCollection 2020. Theranostics. 2020. PMID: 31903136 Free PMC article.
HGSC is characterized by the early and rapid development of metastases accompanied by a high frequency of ascites i.e. the pathological accumulation of fluid in peritoneum. Ascites constitute a complex tumor microenvironment and contribute to disease progression by largely …
HGSC is characterized by the early and rapid development of metastases accompanied by a high frequency of ascites i.e. the pathologic …
Human endogenous retroviruses (HERVs) in breast cancer: altered expression pattern implicates divergent roles in carcinogenesis.
Záveský L, Jandáková E, Weinberger V, Minář L, Kohoutová M, Slanař O. Záveský L, et al. Oncology. 2024 Feb 26. doi: 10.1159/000538021. Online ahead of print. Oncology. 2024. PMID: 38408442
Methods HERVs expression was evaluated to show the differences between breast cancer and control samples, and their associations with clinicopathological parameters. Gene expression of 12 HERVs, i.e. ERVE-4, ERVW-1, ERVFRD-1, ERVV-1, ERV3-1, ERVH48-1, ERVMER34-1, ERVK7, ER …
Methods HERVs expression was evaluated to show the differences between breast cancer and control samples, and their associations with clinic …
CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk.
Lei H, Sjöberg-Margolin S, Salahshor S, Werelius B, Jandáková E, Hemminki K, Lindblom A, Vorechovský I. Lei H, et al. Int J Cancer. 2002 Mar 10;98(2):199-204. doi: 10.1002/ijc.10176. Int J Cancer. 2002. PMID: 11857408 Free article.
Mutations and diminished expression of the E-cadherin gene (CDH1) have been identified in a number of epithelial malignancies. ...
Mutations and diminished expression of the E-cadherin gene (CDH1) have been identified in a number of epithelial malignancies. ...
A Novel Approach to Preoperative Risk Stratification in Endometrial Cancer: The Added Value of Immunohistochemical Markers.
Weinberger V, Bednarikova M, Hausnerova J, Ovesna P, Vinklerova P, Minar L, Felsinger M, Jandakova E, Cihalova M, Zikan M. Weinberger V, et al. Front Oncol. 2019 Apr 12;9:265. doi: 10.3389/fonc.2019.00265. eCollection 2019. Front Oncol. 2019. PMID: 31032226 Free PMC article.

When immunohistochemical markers were included into the current diagnostic model, sensitivity improved (48.4 vs. 75.8%, p < 0.001). PPV was similar for both methods, while NPV (i.e., the probability of extremely low risk in negative test cases) was improved (66 vs. 78.9

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When immunohistochemical markers were included into the current diagnostic model, sensitivity improved (48.4 vs. 75.8%, p < 0.001). PPV w

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