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E and P Selectins as Potential Markers in the Assessment of the Severity of Acute Pancreatitis.
Tsaroucha AK, Schizas D, Vailas MG, Rachmani E, Kanavidis P, Asimakopoulos V, Vlachos S, Sotiropoulou M, Pitiakoudis MS, Simopoulos CE. Tsaroucha AK, et al. Pancreas. 2018 Apr;47(4):406-411. doi: 10.1097/MPA.0000000000001009. Pancreas. 2018. PMID: 29517629

RESULTS: Values of E and P selectins on admission were both elevated compared with control subjects (P < 0.01). The nonsurvivors had higher values of E selectin (P < 0.04) and P selectin (P < 0.03) on admission. Levels of E and P selectin showed posi

…

RESULTS: Values of E and P selectins on admission were both elevated compared with control subjects (P < 0.01). The nonsurvivors h

…
A Comprehensive Review of the Cardiovascular Protective Properties of Silibinin/Silymarin: A New Kid on the Block.
Kadoglou NPE, Panayiotou C, Vardas M, Balaskas N, Kostomitsopoulos NG, Tsaroucha AK, Valsami G. Kadoglou NPE, et al. Pharmaceuticals (Basel). 2022 Apr 27;15(5):538. doi: 10.3390/ph15050538. Pharmaceuticals (Basel). 2022. PMID: 35631363 Free PMC article. Review.
The present comprehensive literature review aimed to critically summarize the pharmacological properties of silymarin extract and its main ingredient silibinin in relation to classical cardiovascular risk factors (e.g., diabetes mellitus, etc.). We also assessed their pote …
The present comprehensive literature review aimed to critically summarize the pharmacological properties of silymarin extract and its main i …
Autotaxin Expression in Hepatocellular Carcinoma.
Memet I, Tsalkidou E, Tsaroucha AK, Lambropoulou M, Chatzaki E, Trypsianis G, Schizas D, Pitiakoudis M, Simopoulos C. Memet I, et al. J Invest Surg. 2018 Oct;31(5):359-365. doi: 10.1080/08941939.2017.1331280. Epub 2017 Jun 9. J Invest Surg. 2018. PMID: 28598712
Silibinin-hydroxypropyl-β-cyclodextrin (SLB-HP-β-CD) complex prevents apoptosis in liver and kidney after hepatic ischemia-reperfusion injury.
Tsaroucha AK, Korovesis GN, Valsami G, Lambropoulou M, Kollaras V, Anagnostopoulos C, Kostomitsopoulos N, Zerbini E, Simopoulos C. Tsaroucha AK, et al. Food Chem Toxicol. 2020 Nov;145:111731. doi: 10.1016/j.fct.2020.111731. Epub 2020 Sep 4. Food Chem Toxicol. 2020. PMID: 32891719
The C and Si groups were each subdivided in four subgroups according to euthanasia times (i.e., 60, 120, 180, 240 min). We assessed expression of caspase-3 and TUNEL assay, and biochemical and histological parameters. ...
The C and Si groups were each subdivided in four subgroups according to euthanasia times (i.e., 60, 120, 180, 240 min). We assessed e …
The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR.
Betsou A, Lambropoulou M, Georgakopoulou AE, Kostomitsopoulos N, Konstandi O, Anagnostopoulos K, Tsalikidis C, Simopoulos CE, Valsami G, Tsaroucha AK. Betsou A, et al. J Pharm Pharmacol. 2021 Aug 12;73(9):1274-1284. doi: 10.1093/jpp/rgab062. J Pharm Pharmacol. 2021. PMID: 33847359
Both groups were further divided into 4 subgroups, based on euthanasia time (i.e., 60, 120, 180 and 240 min). KEY FINDINGS: qRT-PCR results confirmed the statistically significant reduction of the expression of the pro-inflammatory factors at 240 min after I/R injury (tumo …
Both groups were further divided into 4 subgroups, based on euthanasia time (i.e., 60, 120, 180 and 240 min). KEY FINDINGS: qRT-PCR r …
Beneficial effect of an antibody against interleukin-2 receptor (daclizumab) in an experimental model of hepatocyte xenotransplantation.
Papagoras D, Papalois A, Tsaroucha A, Lytras D, Kyriazanos J, Giannakou N, Laftsidis P, Simopoulos C. Papagoras D, et al. World J Gastroenterol. 2007 Mar 7;13(9):1435-7. doi: 10.3748/wjg.v13.i9.1435. World J Gastroenterol. 2007. PMID: 17457977 Free PMC article.
Group A (n = 13): no treatment; Group B (n = 14): FHF and XenoTx; Group C (n = 14): FHF and XenoTx and cyclosporin (CsA); Group D (n = 14): FHF and XenoTx and Dmab; Group E (n = 13): FHF and XenoTx and CsA and Dmab. The rats were followed for 15 d. RESULTS: Statistical ana …
Group A (n = 13): no treatment; Group B (n = 14): FHF and XenoTx; Group C (n = 14): FHF and XenoTx and cyclosporin (CsA); Group D (n = 14): …
13 results