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Page 1
Nanoparticles in Combating Cancer: Opportunities and Limitations. A Brief Review.
Pedziwiatr-Werbicka E, Horodecka K, Shcharbin D, Bryszewska M. Pedziwiatr-Werbicka E, et al. Curr Med Chem. 2021;28(2):346-359. doi: 10.2174/0929867327666200130101605. Curr Med Chem. 2021. PMID: 32000637 Review.
Nanodrugs should be developed that can be effective as an anti-metastatic treatment, e.g. by enhancing the ability of nanoparticles to transport chemotherapeutic loads to sentinel lymph nodes using the immune system and developing chemotherapy in specific metastatic areas. …
Nanodrugs should be developed that can be effective as an anti-metastatic treatment, e.g. by enhancing the ability of nanoparticles t …
Pegylated Gold Nanoparticles Conjugated with siRNA: Complexes Formation and Cytotoxicity.
Okła E, Białecki P, Kędzierska M, Pędziwiatr-Werbicka E, Miłowska K, Takvor S, Gómez R, de la Mata FJ, Bryszewska M, Ionov M. Okła E, et al. Int J Mol Sci. 2023 Apr 2;24(7):6638. doi: 10.3390/ijms24076638. Int J Mol Sci. 2023. PMID: 37047610 Free PMC article.
One significant pharmacological problem is crossing biological barriers by commonly used drugs, e.g., in the treatment of neurodegenerative diseases, which have a problem of the blood-brain barrier (BBB) restricting drug delivery. ...
One significant pharmacological problem is crossing biological barriers by commonly used drugs, e.g., in the treatment of neurodegene …
Synthesis and biophysical evaluation of carbosilane dendrimers as therapeutic siRNA carriers.
Zawadzki S, Martín-Serrano Á, Okła E, Kędzierska M, Garcia-Gallego S, López PO, de la Mata FJ, Michlewska S, Makowski T, Ionov M, Pędziwiatr-Werbicka E, Bryszewska M, Miłowska K. Zawadzki S, et al. Sci Rep. 2024 Jan 18;14(1):1615. doi: 10.1038/s41598-024-51238-w. Sci Rep. 2024. PMID: 38238354 Free PMC article.
In this study, we investigated the biophysical properties of dendrimers and their complexes with siRNA directed against the apolipoprotein E (APOE) gene to identify an appropriate nanocarrier capable of safely delivering the cargo across the BBB. ...
In this study, we investigated the biophysical properties of dendrimers and their complexes with siRNA directed against the apolipoprotein …
The effect of surface modification of dendronized gold nanoparticles on activation and release of pyroptosis-inducing pro-inflammatory cytokines in presence of bacterial lipopolysaccharide in monocytes.
Kuc-Ciepluch D, Gorzkiewicz M, Pędziwiatr-Werbicka E, Barrios-Gumiel A, Lasak M, Mariak A, Sztandera K, Gomez R, de la Mata FJ, Lankoff A, Klajnert-Maculewicz B, Bryszewska M, Arabski M, Ciepluch K. Kuc-Ciepluch D, et al. Colloids Surf B Biointerfaces. 2022 Sep;217:112652. doi: 10.1016/j.colsurfb.2022.112652. Epub 2022 Jun 20. Colloids Surf B Biointerfaces. 2022. PMID: 35772353 Free article.
Role of cationic carbosilane dendrons and metallic core of functionalized gold nanoparticles in their interaction with human serum albumin.
Shcharbin D, Pedziwiatr-Werbicka E, Serchenya T, Cyboran-Mikolajczyk S, Prakhira L, Abashkin V, Dzmitruk V, Ionov M, Loznikova S, Shyrochyna I, Sviridov O, Peña-González CE, Gumiel AB, Gómez R, de la Mata FJ, Bryszewska M. Shcharbin D, et al. Int J Biol Macromol. 2018 Oct 15;118(Pt B):1773-1780. doi: 10.1016/j.ijbiomac.2018.07.023. Epub 2018 Jul 8. Int J Biol Macromol. 2018. PMID: 29997045