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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
2000 1
2002 2
2003 1
2004 2
2007 2
2009 1
2013 1
2014 2
2015 1
2016 1
2017 2
2019 3
2020 2
2021 2
2024 0

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23 results

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Page 1
Embracing model-based designs for dose-finding trials.
Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V. Love SB, et al. Br J Cancer. 2017 Jul 25;117(3):332-339. doi: 10.1038/bjc.2017.186. Epub 2017 Jun 29. Br J Cancer. 2017. PMID: 28664918 Free PMC article. Review.
The most prominent barriers to implementation of a model-based design were lack of suitable training, chief investigators' preference for algorithm-based designs (e.g., 3+3), and limited resources for study design before funding. ...
The most prominent barriers to implementation of a model-based design were lack of suitable training, chief investigators' preference for al …
Factors shaping the delivery of acute inpatient stroke therapy: a narrative synthesis.
Taylor E, McKevitt C, Jones F. Taylor E, et al. J Rehabil Med. 2015 Feb;47(2):107-19. doi: 10.2340/16501977-1918. J Rehabil Med. 2015. PMID: 25437308 Free article. Review.
OBJECTIVE: To investigate factors shaping the delivery of acute inpatient stroke therapy (i.e. occupational therapy, physiotherapy, and speech and language therapy). ...
OBJECTIVE: To investigate factors shaping the delivery of acute inpatient stroke therapy (i.e. occupational therapy, physiotherapy, a …
BAC library of T. pallidum DNA in E. coli.
Smajs D, McKevitt M, Wang L, Howell JK, Norris SJ, Palzkill T, Weinstock GM. Smajs D, et al. Genome Res. 2002 Mar;12(3):515-22. doi: 10.1101/gr.207302. Genome Res. 2002. PMID: 11875041 Free PMC article.
Of mapped clones, 19 were selected to represent the minimal set of E. coli BAC clones covering 1026 of the total 1040 (98.7%) predicted T. pallidum ORFs. Using this minimal set of clones, at least 12 T. pallidum proteins were shown to react with pooled sera from rabbits im …
Of mapped clones, 19 were selected to represent the minimal set of E. coli BAC clones covering 1026 of the total 1040 (98.7%) predict …
The protein network of bacterial motility.
Rajagopala SV, Titz B, Goll J, Parrish JR, Wohlbold K, McKevitt MT, Palzkill T, Mori H, Finley RL Jr, Uetz P. Rajagopala SV, et al. Mol Syst Biol. 2007;3:128. doi: 10.1038/msb4100166. Epub 2007 Jul 31. Mol Syst Biol. 2007. PMID: 17667950 Free PMC article.
To explore the biological relevance of these interactions, we tested an Escherichia coli gene deletion array for motility defects (using swarming assays) and found 159 gene deletion strains to have reduced or no motility. Comparing our interaction data with motility phenotypes fr …
To explore the biological relevance of these interactions, we tested an Escherichia coli gene deletion array for motility defects (using swa …
What underlies the difference between self-reported health and disability after stroke? A qualitative study in the UK.
Mavaddat N, Sadler E, Lim L, Williams K, Warburton E, Kinmonth AL, Mckevitt C, Mant J. Mavaddat N, et al. BMC Neurol. 2021 Aug 13;21(1):315. doi: 10.1186/s12883-021-02338-x. BMC Neurol. 2021. PMID: 34388983 Free PMC article.
Fifteen stroke survivors purposively sampled from the clinic who had discordant self-rated health and levels of disability i.e. reported health as 'excellent' or 'good' despite significant physical disability (eight), or as 'fair' or 'poor' despite minimal disability (seve …
Fifteen stroke survivors purposively sampled from the clinic who had discordant self-rated health and levels of disability i.e. repor …
Longer-term health and social care strategies for stroke survivors and their carers: the LoTS2Care research programme including cluster feasibility RCT.
Forster A, Ozer S, Crocker TF, House A, Hewison J, Roberts E, Dickerson J, Carter G, Hulme C, Fay M, Richardson G, Wright A, McKevitt C, McEachan R, Foy R, Barnard L, Moreau L, Prashar A, Clarke D, Hardicre N, Holloway I, Brindle R, Hall J, Burton LJ, Atkinson R, Hawkins RJ, Brown L, Cornwall N, Dawkins B, Meads D, Schmitt L, Fletcher M, Speed M, Grenfell K, Hartley S, Young J, Farrin A. Forster A, et al. Southampton (UK): NIHR Journals Library; 2021 Mar. Southampton (UK): NIHR Journals Library; 2021 Mar. PMID: 33819000 Free Books & Documents. Review.
OBJECTIVES: The aims were to develop and test a longer-term stroke care strategy focused on improving the quality of life of stroke survivors and their carers by addressing unmet needs, and maintenance and enhancement of participation (i.e. involvement in life situations). …
OBJECTIVES: The aims were to develop and test a longer-term stroke care strategy focused on improving the quality of life of stroke survivor …
Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs.
Kamola PJ, Maratou K, Wilson PA, Rush K, Mullaney T, McKevitt T, Evans P, Ridings J, Chowdhury P, Roulois A, Fairchild A, McCawley S, Cartwright K, Gooderham NJ, Gant TW, Moores K, Hughes SA, Edbrooke MR, Clark K, Parry JD. Kamola PJ, et al. Mol Ther Nucleic Acids. 2017 Sep 15;8:383-394. doi: 10.1016/j.omtn.2017.07.003. Epub 2017 Jul 8. Mol Ther Nucleic Acids. 2017. PMID: 28918038 Free PMC article.
Unfortunately, their therapeutic application, particularly that of the more potent chemistries (e.g., locked-nucleic-acid-containing gapmers), has been hampered by their frequent hepatoxicity, which could be driven by hybridization-mediated interactions. ...To rank ASOs ba …
Unfortunately, their therapeutic application, particularly that of the more potent chemistries (e.g., locked-nucleic-acid-containing …
Evaluation of reconfigurations of acute stroke services in different regions of England and lessons for implementation: a mixed-methods study.
Fulop NJ, Ramsay AIG, Hunter RM, McKevitt C, Perry C, Turner SJ, Boaden R, Papachristou I, Rudd AG, Tyrrell PJ, Wolfe CDA, Morris S. Fulop NJ, et al. Southampton (UK): NIHR Journals Library; 2019 Feb. Southampton (UK): NIHR Journals Library; 2019 Feb. PMID: 30789689 Free Books & Documents. Review.
RESULTS: Impact - the London centralisation performed significantly better than the rest of England (RoE) in terms of mortality [-1.1%, 95% confidence interval (CI) -2.1% to -0.1%], resulting in an estimated additional 96 lives saved per year beyond reductions observed in the RoE …
RESULTS: Impact - the London centralisation performed significantly better than the rest of England (RoE) in terms of mortality [-1.1%, 95% …
Evaluation of an Extended Stroke Rehabilitation Service (EXTRAS): A Randomized Controlled Trial and Economic Analysis.
Rodgers H, Howel D, Bhattarai N, Cant R, Drummond A, Ford GA, Forster A, Francis R, Hills K, Laverty AM, McKevitt C, McMeekin P, Price CIM, Stamp E, Stevens E, Vale L, Shaw L. Rodgers H, et al. Stroke. 2019 Dec;50(12):3561-3568. doi: 10.1161/STROKEAHA.119.024876. Epub 2019 Oct 22. Stroke. 2019. PMID: 31637972 Free PMC article. Clinical Trial.
23 results