Exploring mechanochemical parameters using a DoE approach: Crystal structure solution from synchrotron XRPD and characterization of a new praziquantel polymorph.
Zanolla D, Perissutti B, Vioglio PC, Chierotti MR, Gigli L, Demitri N, Passerini N, Albertini B, Franceschinis E, Keiser J, Voinovich D.
Zanolla D, et al.
Eur J Pharm Sci. 2019 Dec 1;140:105084. doi: 10.1016/j.ejps.2019.105084. Epub 2019 Oct 15.
Eur J Pharm Sci. 2019.
PMID: 31626966
Free article.
Three experimental responses were evaluated on the resulting ground samples: two quantitative responses, i.e. median particle size by Laser Light scattering (LLS) and drug recovery by HPLC, and one qualitative dependent variable, i.e. the obtained PZQ crystalline fo …
Three experimental responses were evaluated on the resulting ground samples: two quantitative responses, i.e. median particle size by …