Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease.
Bettcher BM, Olson KE, Carlson NE, McConnell BV, Boyd T, Adame V, Solano DA, Anton P, Markham N, Thaker AA, Jensen AM, Dallmann EN, Potter H, Coughlan C.
Bettcher BM, et al.
Neurobiol Aging. 2021 Jul;103:68-77. doi: 10.1016/j.neurobiolaging.2021.02.012. Epub 2021 Feb 26.
Neurobiol Aging. 2021.
PMID: 33845398
Free PMC article.
We examined the association between blood GFAP, memory, and white matter (WM) integrity, accounting for blood markers of AD pathology (i.e., Abeta42) and neurodegeneration (i.e., total tau; neurofilament light chain) in 114 older adults (asymptomatic, n = 69; MCI/AD …
We examined the association between blood GFAP, memory, and white matter (WM) integrity, accounting for blood markers of AD pathology (i. …