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Pd-catalyzed C-C and C-N cross-coupling reactions in 2-aminothieno[3,2-d]pyrimidin-4(3H)-one series for antiplasmodial pharmacomodulation.
RSC Adv. 2022 Jul 8;12(31):20004-20021. doi: 10.1039/d2ra01687g. eCollection 2022 Jul 6.
RSC Adv. 2022.
PMID: 35865200
Free PMC article.
Antiplasmodial 2-thiophenoxy-3-trichloromethyl quinoxalines target the apicoplast of Plasmodium falciparum.
Amrane D, Primas N, Arnold CS, Hutter S, Louis B, Sanz-Serrano J, Azqueta A, Amanzougaghene N, Tajeri S, Mazier D, Verhaeghe P, Azas N, Botté C, Vanelle P.
Amrane D, et al.
Eur J Med Chem. 2021 Nov 15;224:113722. doi: 10.1016/j.ejmech.2021.113722. Epub 2021 Jul 29.
Eur J Med Chem. 2021.
PMID: 34364164
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Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-Trichloromethyl Quinazolines.
Amrane D, Gellis A, Hutter S, Prieri M, Verhaeghe P, Azas N, Vanelle P, Primas N.
Amrane D, et al.
Molecules. 2020 Aug 27;25(17):3929. doi: 10.3390/molecules25173929.
Molecules. 2020.
PMID: 32867402
Free PMC article.
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2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum.
Amrane D, Arnold CS, Hutter S, Sanz-Serrano J, Collia M, Azqueta A, Paloque L, Cohen A, Amanzougaghene N, Tajeri S, Franetich JF, Mazier D, Benoit-Vical F, Verhaeghe P, Azas N, Vanelle P, Botté C, Primas N.
Amrane D, et al.
Pharmaceuticals (Basel). 2021 Jul 26;14(8):724. doi: 10.3390/ph14080724.
Pharmaceuticals (Basel). 2021.
PMID: 34451821
Free PMC article.
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