Graft-like plantar lesion secondary to possible dorsal-to-ventral cutaneous transposition

J Am Acad Dermatol. 1999 May;40(5 Pt 1):769-71. doi: 10.1016/s0190-9622(99)70163-5.

Abstract

We describe a 3-year-old male patient with an unusual congenital lesion on the plantar surface of the left foot that had been asymptomatic until shortly before presentation. Histologic examination of the plaque revealed a thinner keratin layer, increased pigmentation, and a pilosebaceous unit with a visible vellus hair. We tentatively hypothesize from this single case that a disruption in the normal sequence of events of morphogenesis, and particularly in dorsal-to-ventral orientation, may have occurred in this patient.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Foot Diseases / congenital*
  • Foot Diseases / pathology
  • Hair / pathology
  • Humans
  • Keratins / analysis
  • Male
  • Morphogenesis
  • Pigmentation Disorders / congenital
  • Pigmentation Disorders / pathology
  • Sebaceous Glands / pathology
  • Skin Abnormalities / pathology*

Substances

  • Keratins