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Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages.
Boytard L, Hadi T, Silvestro M, Qu H, Kumpfbeck A, Sleiman R, Fils KH, Alebrahim D, Boccalatte F, Kugler M, Corsica A, Gelb BE, Jacobowitz G, Miller G, Bellini C, Oakes J, Silvestre JS, Zangi L, Ramkhelawon B. Boytard L, et al. Among authors: alebrahim d. Nat Commun. 2020 Aug 27;11(1):4311. doi: 10.1038/s41467-020-18088-2. Nat Commun. 2020. PMID: 32855420 Free PMC article.
The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice-Brief Report.
Silvestro M, Rivera CF, Alebrahim D, Vlahos J, Pratama MY, Lu C, Tang C, Harpel Z, Sleiman Tellaoui R, Zias AL, Maldonado DJ, Byrd D, Attur M, Mignatti P, Ramkhelawon B. Silvestro M, et al. Among authors: alebrahim d. Arterioscler Thromb Vasc Biol. 2022 Oct;42(10):1244-1253. doi: 10.1161/ATVBAHA.122.317686. Epub 2022 Sep 8. Arterioscler Thromb Vasc Biol. 2022. PMID: 36073351 Free PMC article.
Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells.
Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, Barone K, Spiro W, Hutchison S, Simon R, Rateri D, Pinet F, Fenyo D, Adelman M, Moore KJ, Eltzschig HK, Daugherty A, Ramkhelawon B. Hadi T, et al. Among authors: alebrahim d. Nat Commun. 2018 Nov 27;9(1):5022. doi: 10.1038/s41467-018-07495-1. Nat Commun. 2018. PMID: 30479344 Free PMC article.