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Year Number of Results
1990 1
1995 1
1996 1
1997 1
1998 1
1999 1
2000 2
2001 2
2002 5
2003 7
2004 9
2005 3
2006 7
2007 6
2008 9
2009 11
2010 11
2011 8
2012 17
2013 14
2014 20
2015 28
2016 31
2017 21
2018 33
2019 25
2020 24
2021 16
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2023 20
2024 16

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327 results

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Showing results for dominique target
Your search for Dominique Tarlet retrieved no results
Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics.
Morigny P, Boucher J, Arner P, Langin D. Morigny P, et al. Nat Rev Endocrinol. 2021 May;17(5):276-295. doi: 10.1038/s41574-021-00471-8. Epub 2021 Feb 24. Nat Rev Endocrinol. 2021. PMID: 33627836 Free article. Review.
New challenges include defining the heterogeneity of white adipocytes in different anatomical locations throughout the lifespan and investigating the importance of rhythmic processes. Targeting white fat metabolism offers opportunities for improved patient stratification a …
New challenges include defining the heterogeneity of white adipocytes in different anatomical locations throughout the lifespan and investig …
Advances in Osteosarcoma.
Panez-Toro I, Muñoz-García J, Vargas-Franco JW, Renodon-Cornière A, Heymann MF, Lézot F, Heymann D. Panez-Toro I, et al. Curr Osteoporos Rep. 2023 Aug;21(4):330-343. doi: 10.1007/s11914-023-00803-9. Epub 2023 Jun 17. Curr Osteoporos Rep. 2023. PMID: 37329384 Free PMC article. Review.
PURPOSE OF REVIEW: This article gives a brief overview of the most recent developments in osteosarcoma treatment, including targeting of signaling pathways, immune checkpoint inhibitors, drug delivery strategies as single or combined approaches, and the identification of n …
PURPOSE OF REVIEW: This article gives a brief overview of the most recent developments in osteosarcoma treatment, including targeting …
Cancer stem cells in osteosarcoma.
Brown HK, Tellez-Gabriel M, Heymann D. Brown HK, et al. Cancer Lett. 2017 Feb 1;386:189-195. doi: 10.1016/j.canlet.2016.11.019. Epub 2016 Nov 25. Cancer Lett. 2017. PMID: 27894960 Free article. Review.
Osteosarcoma frequently gains resistance to standard therapies highlighting the need for improved treatment regimens and identification of novel therapeutic targets. Cancer stem cells (CSC) represent a sub-type of tumour cells attributed to critical steps in cancer includi …
Osteosarcoma frequently gains resistance to standard therapies highlighting the need for improved treatment regimens and identification of n …
Sarcoma treatment in the era of molecular medicine.
Grünewald TG, Alonso M, Avnet S, Banito A, Burdach S, Cidre-Aranaz F, Di Pompo G, Distel M, Dorado-Garcia H, Garcia-Castro J, González-González L, Grigoriadis AE, Kasan M, Koelsche C, Krumbholz M, Lecanda F, Lemma S, Longo DL, Madrigal-Esquivel C, Morales-Molina Á, Musa J, Ohmura S, Ory B, Pereira-Silva M, Perut F, Rodriguez R, Seeling C, Al Shaaili N, Shaabani S, Shiavone K, Sinha S, Tomazou EM, Trautmann M, Vela M, Versleijen-Jonkers YM, Visgauss J, Zalacain M, Schober SJ, Lissat A, English WR, Baldini N, Heymann D. Grünewald TG, et al. EMBO Mol Med. 2020 Nov 6;12(11):e11131. doi: 10.15252/emmm.201911131. Epub 2020 Oct 13. EMBO Mol Med. 2020. PMID: 33047515 Free PMC article. Review.
Current multimodal treatment concepts combine surgery, polychemotherapy (with/without local hyperthermia), irradiation, immunotherapy, and/or targeted therapeutics. Recent scientific advancements have enabled a more precise molecular characterization of sarcoma subtypes an …
Current multimodal treatment concepts combine surgery, polychemotherapy (with/without local hyperthermia), irradiation, immunotherapy, and/o …
Resveratrol and Cardiovascular Diseases.
Bonnefont-Rousselot D. Bonnefont-Rousselot D. Nutrients. 2016 May 2;8(5):250. doi: 10.3390/nu8050250. Nutrients. 2016. PMID: 27144581 Free PMC article. Review.
Preclinical studies have made it possible to identify molecular targets (SIRT-1, AMPK, Nrf2, NFkappaB); however, there are limited human clinical trials, and difficulties in the interpretation of results arise from the use of high-dose RES supplements in research studies, …
Preclinical studies have made it possible to identify molecular targets (SIRT-1, AMPK, Nrf2, NFkappaB); however, there are limited hu …
Advances in Risk Classification and Treatment Strategies for Neuroblastoma.
Pinto NR, Applebaum MA, Volchenboum SL, Matthay KK, London WB, Ambros PF, Nakagawara A, Berthold F, Schleiermacher G, Park JR, Valteau-Couanet D, Pearson AD, Cohn SL. Pinto NR, et al. J Clin Oncol. 2015 Sep 20;33(27):3008-17. doi: 10.1200/JCO.2014.59.4648. Epub 2015 Aug 24. J Clin Oncol. 2015. PMID: 26304901 Free PMC article. Review.
Increased knowledge regarding the biology and genetic basis of neuroblastoma has led to the discovery of druggable targets and promising, new therapeutic approaches. Collaborative efforts of institutions and international cooperative groups have led to advances in our unde …
Increased knowledge regarding the biology and genetic basis of neuroblastoma has led to the discovery of druggable targets and promis …
Immunological causes of obsessive-compulsive disorder: is it time for the concept of an "autoimmune OCD" subtype?
Endres D, Pollak TA, Bechter K, Denzel D, Pitsch K, Nickel K, Runge K, Pankratz B, Klatzmann D, Tamouza R, Mallet L, Leboyer M, Prüss H, Voderholzer U, Cunningham JL; ECNP Network Immuno-NeuroPsychiatry; Domschke K, Tebartz van Elst L, Schiele MA. Endres D, et al. Transl Psychiatry. 2022 Jan 10;12(1):5. doi: 10.1038/s41398-021-01700-4. Transl Psychiatry. 2022. PMID: 35013105 Free PMC article. Review.
Subgroups of patients with OCD show elevated proinflammatory cytokines and autoantibodies against targets that include the basal ganglia. In this conceptual review paper, the clinical manifestations, pathophysiological considerations, diagnostic investigations, and treatme …
Subgroups of patients with OCD show elevated proinflammatory cytokines and autoantibodies against targets that include the basal gang …
Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia.
Sebert M, Gachet S, Leblanc T, Rousseau A, Bluteau O, Kim R, Ben Abdelali R, Sicre de Fontbrune F, Maillard L, Fedronie C, Murigneux V, Bellenger L, Naouar N, Quentin S, Hernandez L, Vasquez N, Da Costa M, Prata PH, Larcher L, de Tersant M, Duchmann M, Raimbault A, Trimoreau F, Fenneteau O, Cuccuini W, Gachard N, Auger N, Tueur G, Blanluet M, Gazin C, Souyri M, Langa Vives F, Mendez-Bermudez A, Lapillonne H, Lengline E, Raffoux E, Fenaux P, Adès L, Forcade E, Jubert C, Domenech C, Strullu M, Bruno B, Buchbinder N, Thomas C, Petit A, Leverger G, Michel G, Cavazzana M, Gluckman E, Bertrand Y, Boissel N, Baruchel A, Dalle JH, Clappier E, Gilson E, Deriano L, Chevret S, Sigaux F, Socié G, Stoppa-Lyonnet D, de Thé H, Antoniewski C, Bluteau D, Peffault de Latour R, Soulier J. Sebert M, et al. Cell Stem Cell. 2023 Feb 2;30(2):153-170.e9. doi: 10.1016/j.stem.2023.01.006. Cell Stem Cell. 2023. PMID: 36736290 Free article.
Functionally, MDM4 triplication conferred greater fitness to murine and human primary FA HSPCs, rescued inflammation-mediated bone marrow failure, and drove clonal dominance in FA mouse models, while targeting MDM4 impaired leukemia cells in vitro and in vivo. Our results …
Functionally, MDM4 triplication conferred greater fitness to murine and human primary FA HSPCs, rescued inflammation-mediated bone marrow fa …
Management of endometriosis: CNGOF/HAS clinical practice guidelines - Short version.
Collinet P, Fritel X, Revel-Delhom C, Ballester M, Bolze PA, Borghese B, Bornsztein N, Boujenah J, Brillac T, Chabbert-Buffet N, Chauffour C, Clary N, Cohen J, Decanter C, Denouël A, Dubernard G, Fauconnier A, Fernandez H, Gauthier T, Golfier F, Huchon C, Legendre G, Loriau J, Mathieu-d'Argent E, Merlot B, Niro J, Panel P, Paparel P, Philip CA, Ploteau S, Poncelet C, Rabischong B, Roman H, Rubod C, Santulli P, Sauvan M, Thomassin-Naggara I, Torre A, Wattier JM, Yazbeck C, Bourdel N, Canis M. Collinet P, et al. J Gynecol Obstet Hum Reprod. 2018 Sep;47(7):265-274. doi: 10.1016/j.jogoh.2018.06.003. Epub 2018 Jun 18. J Gynecol Obstet Hum Reprod. 2018. PMID: 29920379 Free article.
First-line diagnostic investigations for endometriosis are physical examination and pelvic ultrasound. The second-line investigations are: targeted pelvic examination performed by an expert clinician, transvaginal ultrasound performed by an expert physician sonographer (ra …
First-line diagnostic investigations for endometriosis are physical examination and pelvic ultrasound. The second-line investigations are: …
Rucaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer Associated with a DNA Damage Repair Gene Alteration: Final Results from the Phase 2 TRITON2 Study.
Abida W, Campbell D, Patnaik A, Bryce AH, Shapiro J, Bambury RM, Zhang J, Burke JM, Castellano D, Font A, Ganju V, Hardy-Bessard AC, McDermott R, Sautois B, Spaeth D, Voog E, Piulats JM, Pintus E, Ryan CJ, Merseburger AS, Daugaard G, Heidenreich A, Fizazi K, Loehr A, Despain D, Simmons AD, Dowson M, Go J, Watkins SP, Chowdhury S. Abida W, et al. Eur Urol. 2023 Sep;84(3):321-330. doi: 10.1016/j.eururo.2023.05.021. Epub 2023 Jun 3. Eur Urol. 2023. PMID: 37277275 Clinical Trial.
327 results