Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger.
Carvalho ND, Arentshorst M, Kooistra R, Stam H, Sagt CM, van den Hondel CA, Ram AF.
Carvalho ND, et al.
Appl Microbiol Biotechnol. 2011 Jan;89(2):357-73. doi: 10.1007/s00253-010-2916-5. Epub 2010 Oct 5.
Appl Microbiol Biotechnol. 2011.
PMID: 20922374
Free PMC article.
To assess the role of ERAD in filamentous fungi, we have examined the consequences of disrupting putative ERAD components in the filamentous fungus Aspergillus niger. Deletion of derA, doaA, hrdC, mifA, or mnsA in A. niger yields viable strains, and with the exception of …
To assess the role of ERAD in filamentous fungi, we have examined the consequences of disrupting putative ERAD components in the filamentous …