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Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence.
Zhdanov DD, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Sokolov NN. Zhdanov DD, et al. Among authors: grishin dv. Cell Immunol. 2018 Sep;331:146-160. doi: 10.1016/j.cellimm.2018.06.008. Epub 2018 Jun 19. Cell Immunol. 2018. PMID: 29935763
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes.
Zhdanov DD, Plyasova AA, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Lobaeva TA, Sokolov NN. Zhdanov DD, et al. Among authors: grishin dv. Biochem Biophys Res Commun. 2019 Feb 12;509(3):790-796. doi: 10.1016/j.bbrc.2018.12.186. Epub 2019 Jan 4. Biochem Biophys Res Commun. 2019. PMID: 30612734
Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes.
Zhdanov DD, Pokrovsky VS, Pokrovskaya MV, Alexandrova SS, Eldarov MA, Grishin DV, Basharov MM, Gladilina YA, Podobed OV, Sokolov NN. Zhdanov DD, et al. Among authors: grishin dv. Cancer Med. 2017 Nov;6(11):2697-2712. doi: 10.1002/cam4.1218. Epub 2017 Oct 5. Cancer Med. 2017. PMID: 28984046 Free PMC article.