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Lignan from thyme possesses inhibitory effect on ASIC3 channel current.
Dubinnyi MA, Osmakov DI, Koshelev SG, Kozlov SA, Andreev YA, Zakaryan NA, Dyachenko IA, Bondarenko DA, Arseniev AS, Grishin EV. Dubinnyi MA, et al. Among authors: bondarenko da. J Biol Chem. 2012 Sep 21;287(39):32993-3000. doi: 10.1074/jbc.M112.366427. Epub 2012 Aug 1. J Biol Chem. 2012. PMID: 22854960 Free PMC article.
Sea anemone peptide with uncommon β-hairpin structure inhibits acid-sensing ion channel 3 (ASIC3) and reveals analgesic activity.
Osmakov DI, Kozlov SA, Andreev YA, Koshelev SG, Sanamyan NP, Sanamyan KE, Dyachenko IA, Bondarenko DA, Murashev AN, Mineev KS, Arseniev AS, Grishin EV. Osmakov DI, et al. Among authors: bondarenko da. J Biol Chem. 2013 Aug 9;288(32):23116-27. doi: 10.1074/jbc.M113.485516. Epub 2013 Jun 25. J Biol Chem. 2013. PMID: 23801332 Free PMC article.