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PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis.
Vulfius CA, Lebedev DS, Kryukova EV, Kudryavtsev DS, Kolbaev SN, Utkin YN, Tsetlin VI. Vulfius CA, et al. Among authors: lebedev ds. J Neurochem. 2020 Nov;155(3):274-284. doi: 10.1111/jnc.15020. Epub 2020 Apr 19. J Neurochem. 2020. PMID: 32248535 Free article.