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Silver(I) 1,10-Phenanthroline Complexes Are Active against Fonsecaea pedrosoi Viability and Negatively Modulate Its Potential Virulence Attributes.
Sousa IS, Vieira TDP, Menna-Barreto RFS, Guimarães AJ, McCarron P, McCann M, Devereux M, Santos ALS, Kneipp LF. Sousa IS, et al. J Fungi (Basel). 2023 Mar 15;9(3):356. doi: 10.3390/jof9030356. J Fungi (Basel). 2023. PMID: 36983524 Free PMC article.
This work aimed to evaluate the effects of copper(II), manganese(II) and silver(I) complexes coordinated with 1,10-phenanthroline (phen)/1,10-phenanthroline-5,6-dione (phendione) on Fonsecaea spp. Our results revealed that most of these complexes were able to inhibit F. pe …
This work aimed to evaluate the effects of copper(II), manganese(II) and silver(I) complexes coordinated with 1,10-phenanthroline (phen)/1,1 …
1-Benzyl-2,5-dioxopyrrolidine-3,4-diyl diacetate.
Caracelli I, Ferreira FP, Vieira AS, Stefani HA, De Simone CA, Tiekink ER. Caracelli I, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 6;66(Pt 12):o3044. doi: 10.1107/S1600536810043187. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21589357 Free PMC article.
The pyrrolidine-2,5-dione ring in the title compound, C(15)H(15)NO(6), is in a twisted conformation with the acetyl C atoms projecting to opposite sides of the ring. ...
The pyrrolidine-2,5-dione ring in the title compound, C(15)H(15)NO(6), is in a twisted conformation with the acetyl C atoms projectin …
Theoretical and Experimental Investigation of Acidity of the Glutamate Receptor Antagonist 6,7-Dinitro-1,4-dihydroquinoxaline-2,3-dione and Its Possible Implication in GluA2 Binding.
de Freitas GRS, Coelho SE, Monteiro NKV, Neri JM, Cavalcanti LN, Domingos JB, Vieira DS, de Souza MAF, Menezes FG. de Freitas GRS, et al. J Phys Chem A. 2017 Oct 5;121(39):7414-7423. doi: 10.1021/acs.jpca.7b07775. Epub 2017 Sep 25. J Phys Chem A. 2017. PMID: 28902515
This paper presents an experimental/theoretical combined investigation on the acid dissociation of the compound 6,7-dinitro-1,4-dihydroquinoxaline-2,3-dione (DNQX), a well-established antagonist of ionotropic glutamate receptor GluA2. ...
This paper presents an experimental/theoretical combined investigation on the acid dissociation of the compound 6,7-dinitro-1,4-dihydroquino …
UHPLC Quantitation Method for New Thiazolidinedione LPSF/GQ-02 and In Vitro/In Vivo Kinetic Studies.
Vieira CM, Campos ML, Padilha EC, Pitta M, Pitta ID, de Lima MD, Peccinini RG. Vieira CM, et al. Drug Metab Lett. 2016;10(3):206-212. doi: 10.2174/1872312810666160725124554. Drug Metab Lett. 2016. PMID: 27456668
METHODS: For this purpose a bioanalytical method for the quantitation of 5-(4- Chloro-benzylidene)-3-(4-methylbenzyl)-thiazolidine-2,4-dione (LPSF/GQ-02) was developed and validated. A Waters UPLC chromatographer using a BEH column (2.1x50mm, 1.7mum particle), mobile phase …
METHODS: For this purpose a bioanalytical method for the quantitation of 5-(4- Chloro-benzylidene)-3-(4-methylbenzyl)-thiazolidine-2,4-di
Coordination of lapachol to bismuth(III) improves its anti-inflammatory and anti-angiogenic activities.
Parrilha GL, Vieira RP, Campos PP, Silva GD, Duarte LP, Andrade SP, Beraldo H. Parrilha GL, et al. Biometals. 2012 Feb;25(1):55-62. doi: 10.1007/s10534-011-9481-y. Epub 2011 Aug 6. Biometals. 2012. PMID: 21822673
Complex [Bi(Lp)(2)]Cl was obtained with 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione, "lapachol" (HLp). Lapachol, [Bi(Lp)(2)]Cl and BiCl(3) were evaluated in a murine model of inflammatory angiogenesis induced by subcutaneous implantation of polyether polyurethane …
Complex [Bi(Lp)(2)]Cl was obtained with 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione, "lapachol" (HLp). Lapachol, [Bi(Lp)(2) …
PI3Kγ deficiency enhances seizures severity and associated outcomes in a mouse model of convulsions induced by intrahippocampal injection of pilocarpine.
Lima IV, Campos AC, Miranda AS, Vieira ÉL, Amaral-Martins F, Vago JP, Santos RP, Sousa LP, Vieira LB, Teixeira MM, Fiebich BL, Moraes MF, Teixeira AL, de Oliveira AC. Lima IV, et al. Exp Neurol. 2015 May;267:123-34. doi: 10.1016/j.expneurol.2015.02.021. Epub 2015 Mar 5. Exp Neurol. 2015. PMID: 25749189
Human accidents involving Rhinocricus spp., a common millipede genus observed in urban areas of Brazil.
De Capitani EM, Vieira RJ, Bucaretchi F, Fernandes LC, Toledo AS, Camargo AC. De Capitani EM, et al. Clin Toxicol (Phila). 2011 Mar;49(3):187-90. doi: 10.3109/15563650.2011.560855. Clin Toxicol (Phila). 2011. PMID: 21495889
Analysis of the content of 50 glands of these animals captured in the southeast region of Brazil identified 2-methil-1,4-benzoquinone and 3,3a,4,5-tetrahydro-1H-pyrrolo-[2,3-b] pyridine-2,6-dione as the substances responsible for the lesions. Benzoquinones are strongly irr …
Analysis of the content of 50 glands of these animals captured in the southeast region of Brazil identified 2-methil-1,4-benzoquinone and 3, …