Diane V. Lefley - Search Results

Year	Number of Results
2008	2
2009	1
2010	3
2012	1
2014	1
2016	1
2017	2
2019	2
2021	2
2022	1
2024	0

1

Novel Methods of Targeting IL-1 Signalling for the Treatment of Breast Cancer Bone Metastasis.

Zhou J, Down JM, George CN, Murphy J, Lefley DV, Tulotta C, Alsharif MA, Leach M, Ottewell PD. Zhou J, et al. Among authors: lefley dv. Cancers (Basel). 2022 Oct 1;14(19):4816. doi: 10.3390/cancers14194816. Cancers (Basel). 2022. PMID: 36230739 Free PMC article.

2

Oestradiol Contributes to Differential Antitumour Effects of Adjuvant Zoledronic Acid Observed Between Pre- and Post-Menopausal Women.

Canuas-Landero VG, George CN, Lefley DV, Corness H, Muthana M, Wilson C, Ottewell PD. Canuas-Landero VG, et al. Among authors: lefley dv. Front Endocrinol (Lausanne). 2021 Oct 18;12:749428. doi: 10.3389/fendo.2021.749428. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34733240 Free PMC article.

3

Endogenous Production of IL1B by Breast Cancer Cells Drives Metastasis and Colonization of the Bone Microenvironment.

Tulotta C, Lefley DV, Freeman K, Gregory WM, Hanby AM, Heath PR, Nutter F, Wilkinson JM, Spicer-Hadlington AR, Liu X, Bradbury SMJ, Hambley L, Cookson V, Allocca G, Kruithof de Julio M, Coleman RE, Brown JE, Holen I, Ottewell PD. Tulotta C, et al. Among authors: lefley dv. Clin Cancer Res. 2019 May 1;25(9):2769-2782. doi: 10.1158/1078-0432.CCR-18-2202. Epub 2019 Jan 22. Clin Cancer Res. 2019. PMID: 30670488 Free article.

4

IL-1 drives breast cancer growth and bone metastasis in vivo.

Holen I, Lefley DV, Francis SE, Rennicks S, Bradbury S, Coleman RE, Ottewell P. Holen I, et al. Among authors: lefley dv. Oncotarget. 2016 Nov 15;7(46):75571-75584. doi: 10.18632/oncotarget.12289. Oncotarget. 2016. PMID: 27765923 Free PMC article.

5

Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.

English WR, Lunt SJ, Fisher M, Lefley DV, Dhingra M, Lee YC, Bingham K, Hurrell JE, Lyons SK, Kanthou C, Tozer GM. English WR, et al. Among authors: lefley dv. Cancer Res. 2017 May 15;77(10):2633-2646. doi: 10.1158/0008-5472.CAN-16-0255. Epub 2017 Apr 4. Cancer Res. 2017. PMID: 28377452 Free article.

6

IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer.

Tulotta C, Lefley DV, Moore CK, Amariutei AE, Spicer-Hadlington AR, Quayle LA, Hughes RO, Ahmed K, Cookson V, Evans CA, Vadakekolathu J, Heath P, Francis S, Pinteaux E, Pockley AG, Ottewell PD. Tulotta C, et al. Among authors: lefley dv. NPJ Breast Cancer. 2021 Jul 21;7(1):95. doi: 10.1038/s41523-021-00305-w. NPJ Breast Cancer. 2021. PMID: 34290237 Free PMC article.

7

Pharmacological inhibition of the IKKε/TBK-1 axis potentiates the anti-tumour and anti-metastatic effects of Docetaxel in mouse models of breast cancer.

Bishop RT, Marino S, de Ridder D, Allen RJ, Lefley DV, Sims AH, Wang N, Ottewell PD, Idris AI. Bishop RT, et al. Among authors: lefley dv. Cancer Lett. 2019 May 28;450:76-87. doi: 10.1016/j.canlet.2019.02.032. Epub 2019 Feb 18. Cancer Lett. 2019. PMID: 30790681 Free article.

8

Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristics.

Kanthou C, Dachs GU, Lefley DV, Steele AJ, Coralli-Foxon C, Harris S, Greco O, Dos Santos SA, Reyes-Aldasoro CC, English WR, Tozer GM. Kanthou C, et al. Among authors: lefley dv. PLoS One. 2014 Aug 13;9(8):e104015. doi: 10.1371/journal.pone.0104015. eCollection 2014. PLoS One. 2014. PMID: 25119572 Free PMC article.

9

Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo.

Holen I, Whitworth J, Nutter F, Evans A, Brown HK, Lefley DV, Barbaric I, Jones M, Ottewell PD. Holen I, et al. Among authors: lefley dv. Breast Cancer Res. 2012 May 25;14(3):R86. doi: 10.1186/bcr3201. Breast Cancer Res. 2012. PMID: 22632416 Free PMC article.

10

Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone.

Ottewell PD, Woodward JK, Lefley DV, Evans CA, Coleman RE, Holen I. Ottewell PD, et al. Among authors: lefley dv. Mol Cancer Ther. 2009 Oct;8(10):2821-32. doi: 10.1158/1535-7163.MCT-09-0462. Epub 2009 Sep 29. Mol Cancer Ther. 2009. PMID: 19789217

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