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G protein-coupled receptor 183 mediates the sensitization of Burkitt lymphoma tumors to CD47 immune checkpoint blockade by anti-CD20/PI3Kδi dual therapy.
Ribeiro ML, Profitós-Pelejà N, Santos JC, Blecua P, Reyes-Garau D, Armengol M, Fernández-Serrano M, Miskin HP, Bosch F, Esteller M, Normant E, Roué G. Ribeiro ML, et al. Among authors: reyes garau d. Front Immunol. 2023 Apr 21;14:1130052. doi: 10.3389/fimmu.2023.1130052. eCollection 2023. Front Immunol. 2023. PMID: 37153563 Free PMC article.
Constitutive Activation of p62/Sequestosome-1-Mediated Proteaphagy Regulates Proteolysis and Impairs Cell Death in Bortezomib-Resistant Mantle Cell Lymphoma.
Quinet G, Xolalpa W, Reyes-Garau D, Profitós-Pelejà N, Azkargorta M, Ceccato L, Gonzalez-Santamarta M, Marsal M, Andilla J, Aillet F, Bosch F, Elortza F, Loza-Alvarez P, Sola B, Coux O, Matthiesen R, Roué G, Rodriguez MS. Quinet G, et al. Among authors: reyes garau d. Cancers (Basel). 2022 Feb 12;14(4):923. doi: 10.3390/cancers14040923. Cancers (Basel). 2022. PMID: 35205670 Free PMC article.
NFAT5 Amplifies Antipathogen Responses by Enhancing Chromatin Accessibility, H3K27 Demethylation, and Transcription Factor Recruitment.
Lunazzi G, Buxadé M, Riera-Borrull M, Higuera L, Bonnin S, Huerga Encabo H, Gaggero S, Reyes-Garau D, Company C, Cozzuto L, Ponomarenko J, Aramburu J, López-Rodríguez C. Lunazzi G, et al. Among authors: reyes garau d. J Immunol. 2021 Jun 1;206(11):2652-2667. doi: 10.4049/jimmunol.2000624. Epub 2021 May 24. J Immunol. 2021. PMID: 34031145 Free PMC article.
R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.
Mendoza P, Martínez-Martín N, Bovolenta ER, Reyes-Garau D, Hernansanz-Agustín P, Delgado P, Diaz-Muñoz MD, Oeste CL, Fernández-Pisonero I, Castellano E, Martínez-Ruiz A, Alonso-Lopez D, Santos E, Bustelo XR, Kurosaki T, Alarcón B. Mendoza P, et al. Among authors: reyes garau d. Sci Signal. 2018 May 29;11(532):eaal1506. doi: 10.1126/scisignal.aal1506. Sci Signal. 2018. PMID: 29844052
Antitumor Activity of the Novel BTK Inhibitor TG-1701 Is Associated with Disruption of Ikaros Signaling in Patients with B-cell Non-Hodgkin Lymphoma.
Ribeiro ML, Reyes-Garau D, Vinyoles M, Profitós Pelejà N, Santos JC, Armengol M, Fernández-Serrano M, Sedó Mor A, Bech-Serra JJ, Blecua P, Musulen E, De La Torre C, Miskin H, Esteller M, Bosch F, Menéndez P, Normant E, Roué G. Ribeiro ML, et al. Among authors: reyes garau d. Clin Cancer Res. 2021 Dec 1;27(23):6591-6601. doi: 10.1158/1078-0432.CCR-21-1067. Epub 2021 Sep 22. Clin Cancer Res. 2021. PMID: 34551904 Free PMC article.
First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases.
Borroto A, Reyes-Garau D, Jiménez MA, Carrasco E, Moreno B, Martínez-Pasamar S, Cortés JR, Perona A, Abia D, Blanco S, Fuentes M, Arellano I, Lobo J, Heidarieh H, Rueda J, Esteve P, Cibrián D, Martinez-Riaño A, Mendoza P, Prieto C, Calleja E, Oeste CL, Orfao A, Fresno M, Sánchez-Madrid F, Alcamí A, Bovolenta P, Martín P, Villoslada P, Morreale A, Messeguer A, Alarcon B. Borroto A, et al. Among authors: reyes garau d. Sci Transl Med. 2016 Dec 21;8(370):370ra184. doi: 10.1126/scitranslmed.aaf2140. Sci Transl Med. 2016. PMID: 28003549