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Showing results for dex in duan
Search for Dexin Duan instead (1 results)
Inflammation and immune cell abnormalities in intracranial aneurysm subarachnoid hemorrhage (SAH): Relevant signaling pathways and therapeutic strategies.
Jin J, Duan J, Du L, Xing W, Peng X, Zhao Q. Jin J, et al. Front Immunol. 2022 Nov 23;13:1027756. doi: 10.3389/fimmu.2022.1027756. eCollection 2022. Front Immunol. 2022. PMID: 36505409 Free PMC article. Review.
In addition, we also summarized potential therapeutic drugs targeting the aneurysm SAH immune inflammatory responses, such as nimodipine, dexmedetomidine (DEX), fingolimod, and genomic variation-related aneurysm prophylactic agent sunitinib. ...
In addition, we also summarized potential therapeutic drugs targeting the aneurysm SAH immune inflammatory responses, such as nimodipine, de …
Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.
Li H, Ren J, Cui H, Wang D, Zhao R, Liu X, Tian S, Wang J, Zhang J, Li P, Thorne RF, Duan S. Li H, et al. Cell Transplant. 2023 Jan-Dec;32:9636897231177356. doi: 10.1177/09636897231177356. Cell Transplant. 2023. PMID: 37265069 Free PMC article.
Glaucoma is a serious complication of glucocorticoid (GC) therapy arising through elevations in intraocular pressure (IOP). Dexamethasone (DEX) is reported to contribute to elevated IOP through different effects on the trabecular meshwork but whether DEX contributes …
Glaucoma is a serious complication of glucocorticoid (GC) therapy arising through elevations in intraocular pressure (IOP). Dexamethasone ( …
MRI-visible mesoporous polydopamine nanoparticles with enhanced antioxidant capacity for osteoarthritis therapy.
Liu S, Zhang C, Zhou Y, Zhang F, Duan X, Liu Y, Zhao X, Liu J, Shuai X, Wang J, Cao Z. Liu S, et al. Biomaterials. 2023 Apr;295:122030. doi: 10.1016/j.biomaterials.2023.122030. Epub 2023 Jan 31. Biomaterials. 2023. PMID: 36758340
Herein, mesoporous polydopamine nanoparticles (DAMM NPs) doped with arginine and manganese (Mn) ions were prepared to load dexamethasone (DEX) for OA intervention. A series of in vitro studies showed that the sustained release of DEX from DAMM NPs suppressed synovia …
Herein, mesoporous polydopamine nanoparticles (DAMM NPs) doped with arginine and manganese (Mn) ions were prepared to load dexamethasone ( …
Dexamethasone reduces autoantibody levels in MRL/lpr mice by inhibiting Tfh cell responses.
Shen C, Xue X, Zhang X, Wu L, Duan X, Su C. Shen C, et al. J Cell Mol Med. 2021 Sep;25(17):8329-8337. doi: 10.1111/jcmm.16785. Epub 2021 Jul 28. J Cell Mol Med. 2021. PMID: 34318604 Free PMC article.
However, the effect of Dex on T follicular helper (Tfh) cells is less documented. Here, using the MRL/lpr mouse model, we investigated the influence of Dex on Tfh cells and potential underlying mechanisms. ...Our data indicate that Dex can be used as a Tfh ce …
However, the effect of Dex on T follicular helper (Tfh) cells is less documented. Here, using the MRL/lpr mouse model, we investigate …
Dexamethasone distribution characteristic following controllable continuous sub-tenon drug delivery in rabbit.
Huang X, Peng M, Yang Y, Duan Y, Li K, Liu S, Ye C, Lin D. Huang X, et al. Drug Deliv. 2017 Nov;24(1):818-824. doi: 10.1080/10717544.2017.1324531. Drug Deliv. 2017. PMID: 28509581 Free PMC article.
High levels of DEX were maintained at 12 h in the ocular tissue immediately after the administration. ...Thus, CCSDD is an effective method of delivering DEX into anterior and posterior segment of the eye....
High levels of DEX were maintained at 12 h in the ocular tissue immediately after the administration. ...Thus, CCSDD is an effective …
Safety, Pharmacokinetics/Pharmacodynamics, and Absolute Bioavailability of Dexmedetomidine Hydrochloride Nasal Spray in Healthy Subjects: A Randomized, Parallel, Escalating Dose Study.
Kuang Y, Wang SY, Wang MN, Yang GP, Guo C, Yang S, Zhang XF, Yang XY, Pei Q, Zou C, He YH, Zhou YY, Duan KM, Huang J. Kuang Y, et al. Front Pharmacol. 2022 May 20;13:871492. doi: 10.3389/fphar.2022.871492. eCollection 2022. Front Pharmacol. 2022. PMID: 35668951 Free PMC article.
Methods: Part 1: a double-blind, placebo-controlled, single ascending dose study was performed on 48 subjects. For 20-/40-mug groups, every 6/2 subjects received either Dex/placebo nasal spray or Dex/placebo injection in two periods. In total, 12/4 subjects each rec …
Methods: Part 1: a double-blind, placebo-controlled, single ascending dose study was performed on 48 subjects. For 20-/40-mug groups, every …
Dexmedetomidine regulate the malignancy of breast cancer cells by activating α2-adrenoceptor/ERK signaling pathway.
Xia M, Ji NN, Duan ML, Tong JH, Xu JG, Zhang YM, Wang SH. Xia M, et al. Eur Rev Med Pharmacol Sci. 2016 Aug;20(16):3500-6. Eur Rev Med Pharmacol Sci. 2016. PMID: 27608913 Free article.
OBJECTIVE: Breast cancer is one of the most aggressive and pervasive cancers identified in females. Dexmedetomidine (Dex) is an efficient anesthetic used in surgery. Our study aimed to explore the role of Dex in the malignancy of breast cancer cells in vitro and in …
OBJECTIVE: Breast cancer is one of the most aggressive and pervasive cancers identified in females. Dexmedetomidine (Dex) is an effic …
Dexmedetomidine Inhibits Gasdermin D-Induced Pyroptosis via the PI3K/AKT/GSK3β Pathway to Attenuate Neuroinflammation in Early Brain Injury After Subarachnoid Hemorrhage in Rats.
Wei B, Liu W, Jin L, Guo S, Fan H, Jin F, Wei C, Fang D, Zhang X, Su S, Duan C, Li X. Wei B, et al. Front Cell Neurosci. 2022 Jun 21;16:899484. doi: 10.3389/fncel.2022.899484. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35800132 Free PMC article.
Previous reports suggest that SAH-induced brain edema, cell apoptosis, and neuronal injury could be suppressed by dexmedetomidine (Dex). In this study, we used a rat model of SAH to investigate the effect of Dex on pyroptosis in EBI after SAH and to determine the me …
Previous reports suggest that SAH-induced brain edema, cell apoptosis, and neuronal injury could be suppressed by dexmedetomidine (Dex …
Functional characterization of the citrus canker susceptibility gene CsLOB1.
Duan S, Jia H, Pang Z, Teper D, White F, Jones J, Zhou C, Wang N. Duan S, et al. Mol Plant Pathol. 2018 Feb 20;19(8):1908-16. doi: 10.1111/mpp.12667. Online ahead of print. Mol Plant Pathol. 2018. PMID: 29461671 Free PMC article.
Pustule formation was not observed in DEX-treated wild-type plants and in non-treated CsLOB1-GR transgenic plants. ...Weaker water soaking was observed with pustule formation in CsLOB1-GR transgenic plants following DEX treatment. When CsLOB1-GR-transgenic Duncan gr …
Pustule formation was not observed in DEX-treated wild-type plants and in non-treated CsLOB1-GR transgenic plants. ...Weaker water so …
52 results