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Showing results for dex in tian
Search for Dexin Tian instead (1 results)
Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates.
Meng QF, Tai W, Tian M, Zhuang X, Pan Y, Lai J, Xu Y, Xu Z, Li M, Zhao G, Yu GT, Yu G, Chen R, Jin N, Li X, Cheng G, Chen X, Rao L. Meng QF, et al. Sci Adv. 2023 Jun 16;9(24):eadg3277. doi: 10.1126/sciadv.adg3277. Epub 2023 Jun 14. Sci Adv. 2023. PMID: 37315135 Free PMC article.
Dexamethasone (DEX) is the first drug to show life-saving efficacy in patients with severe coronavirus disease 2019 (COVID-19), while DEX is associated with serious adverse effects. ...The nanoDEX, made by encapsulating DEX with the iSEND, efficiently promote …
Dexamethasone (DEX) is the first drug to show life-saving efficacy in patients with severe coronavirus disease 2019 (COVID-19), while …
Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis.
Li H, Ren J, Cui H, Wang D, Zhao R, Liu X, Tian S, Wang J, Zhang J, Li P, Thorne RF, Duan S. Li H, et al. Cell Transplant. 2023 Jan-Dec;32:9636897231177356. doi: 10.1177/09636897231177356. Cell Transplant. 2023. PMID: 37265069 Free PMC article.
Glaucoma is a serious complication of glucocorticoid (GC) therapy arising through elevations in intraocular pressure (IOP). Dexamethasone (DEX) is reported to contribute to elevated IOP through different effects on the trabecular meshwork but whether DEX contributes …
Glaucoma is a serious complication of glucocorticoid (GC) therapy arising through elevations in intraocular pressure (IOP). Dexamethasone ( …
Dexamethasone inhibits pancreatic tumor growth in preclinical models: Involvement of activating glucocorticoid receptor.
Yao Y, Yao QY, Xue JS, Tian XY, An QM, Cui LX, Xu C, Su H, Yang L, Feng YY, Hao CY, Zhou TY. Yao Y, et al. Toxicol Appl Pharmacol. 2020 Aug 15;401:115118. doi: 10.1016/j.taap.2020.115118. Epub 2020 Jul 1. Toxicol Appl Pharmacol. 2020. PMID: 32619553
DEX was less potent, however, in SW1990 cells with poor GR expression. Our findings suggest that DEX effectively inhibits pancreatic tumor growth partially through GR activation. ...
DEX was less potent, however, in SW1990 cells with poor GR expression. Our findings suggest that DEX effectively inhibits panc …
Changes in gap junction proteins Connexin30.2 and Connexin40 expression in the sinoatrial node of rats with dexmedetomidine-induced sinus bradycardia.
Yin YQ, Zhong Y, Zhu Y, Tian L. Yin YQ, et al. Braz J Anesthesiol. 2022 Nov-Dec;72(6):768-773. doi: 10.1016/j.bjane.2022.05.004. Epub 2022 May 23. Braz J Anesthesiol. 2022. PMID: 35618083 Free PMC article.
BACKGROUND: Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. ...RESULTS: The expression of Cx30.2 increased, whereas the expression of Cx40 decreased within the sinoatrial node of rats with Dex-induced sinus bradycardia. Atropine …
BACKGROUND: Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. ...RESULTS: The expression of Cx30. …
Role of Teriparatide in Glucocorticoid-induced Osteoporosis through Regulating Cellular Reactive Oxygen Species.
Wang T, Han C, Tian P, Li PF, Ma XL. Wang T, et al. Orthop Surg. 2018 May;10(2):152-159. doi: 10.1111/os.12369. Epub 2018 May 10. Orthop Surg. 2018. PMID: 29745033 Free PMC article.
METHODS: We performed the DCFH-DA assay to investigate the role of ROS in MLO-Y4 cells caused by dexamethasone (Dex). Four groups were included: Dex group, Dex+NAC, Dex+ teriparatide group and control group (without any dispose). ...However, the Dex …
METHODS: We performed the DCFH-DA assay to investigate the role of ROS in MLO-Y4 cells caused by dexamethasone (Dex). Four groups wer …
Dexmedetomidine promotes inflammation resolving through TGF-β1 secreted by F4/80+Ly6G+ macrophage.
Li LC, Tian Y, Xiao J, Yang Y, Wu JN, Chen Y, Zhang PH, Gao-Smith F, Wang JG, Jin SW. Li LC, et al. Int Immunopharmacol. 2021 Jun;95:107480. doi: 10.1016/j.intimp.2021.107480. Epub 2021 Mar 3. Int Immunopharmacol. 2021. PMID: 33676148
However, whether DEX interferes with the inflammation resolving remains unclear. ...DEX markedly increased the F4/80(+)Ly6G(+) macrophage population. ...
However, whether DEX interferes with the inflammation resolving remains unclear. ...DEX markedly increased the F4/80(+)Ly6G(+) …
Postoperative infusion of dexmedetomidine via intravenous patient-controlled analgesia for prevention of postoperative delirium in elderly patients undergoing surgery.
Xie K, Chen J, Tian L, Gu F, Pan Y, Huang Z, Fang J, Yu W, Zhou H. Xie K, et al. Aging Clin Exp Res. 2023 Oct;35(10):2137-2144. doi: 10.1007/s40520-023-02497-6. Epub 2023 Jul 20. Aging Clin Exp Res. 2023. PMID: 37470916 Free PMC article. Clinical Trial.
AIM: We researched whether postoperative infusion of dexmedetomidine (DEX) had prophylactic effect on POD in elderly patients. METHODS: A total of 236 patients over the age of 60 years undergoing thoracoabdominal tumor surgery were enrolled in Zhejiang Cancer Hospital from …
AIM: We researched whether postoperative infusion of dexmedetomidine (DEX) had prophylactic effect on POD in elderly patients. METHOD …
Dexmedetomidine postconditioning attenuates myocardial ischemia/reperfusion injury by activating the Nrf2/Sirt3/SOD2 signaling pathway in the rats.
Hu B, Tian T, Li XT, Hao PP, Liu WC, Chen YG, Jiang TY, Chen PS, Cheng Y, Xue FS. Hu B, et al. Redox Rep. 2023 Dec;28(1):2158526. doi: 10.1080/13510002.2022.2158526. Redox Rep. 2023. PMID: 36738240 Free PMC article.
METHODS: One-hundred forty-seven male Sprague-Dawley rats were randomly divided into five groups receiving the different treatments: Sham, ischemia/reperfusion (I/R), Dex, Brusatol, Dex + Brusatol. By the in vivo rat model of myocardial IRI, cardioprotective effects …
METHODS: One-hundred forty-seven male Sprague-Dawley rats were randomly divided into five groups receiving the different treatments: Sham, i …
Dexamethasone enhances the efficacy of atorvastatin in inhibiting excessively inflammation-induced abnormal angiogenesis by regulating macrophages.
Gong Z, Zhan D, Nie M, Li X, Gao C, Liu X, Xiang T, Yuan J, Jiang W, Huang J, Quan W, Wang D, Tian Y, Yuan H, Zhang J, Jiang R. Gong Z, et al. J Neuroinflammation. 2021 Sep 15;18(1):203. doi: 10.1186/s12974-021-02257-1. J Neuroinflammation. 2021. PMID: 34526068 Free PMC article.
RESULTS: ATO was detected in haematoma fluids and serum samples, whose levels were increased significantly in samples collected from patients treated with both ATO and DEX. ATO was also increased in cultured macrophages treated with ATO and DEX. ...DEX enhanc …
RESULTS: ATO was detected in haematoma fluids and serum samples, whose levels were increased significantly in samples collected from patient …
Melittin promotes dexamethasone in the treatment of adjuvant rheumatoid arthritis in rats.
Yang L, He X, Zhi D, Xue Y, Gong X, Dong K, Tian Y. Yang L, et al. Front Pharmacol. 2024 Feb 13;15:1338432. doi: 10.3389/fphar.2024.1338432. eCollection 2024. Front Pharmacol. 2024. PMID: 38414737 Free PMC article.
The purpose of this study was to explore the role of MLT in the treatment of RA by DEX as well as to clarify the influence of MLT on the efficacy and side effects of DEX. ...Conclusion: Thus, MLT promoted the efficacy of DEX in adjuvant RA treatment in rats, …
The purpose of this study was to explore the role of MLT in the treatment of RA by DEX as well as to clarify the influence of MLT on …
108 results