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Showing results for dex in gan
Search for Dexin Gan instead (1 results)
Dexamethasone protects against Aspergillus fumigatus-induced severe asthma via modulating pulmonary immunometabolism.
Gan PXL, Liao W, Lim HF, Wong WSF. Gan PXL, et al. Pharmacol Res. 2023 Oct;196:106929. doi: 10.1016/j.phrs.2023.106929. Epub 2023 Sep 15. Pharmacol Res. 2023. PMID: 37717682 Free article.
Dex markedly reduced Af-induced eosinophilic airway inflammation, which was coupled with an overall reduction in lung glycolysis, glutaminolysis, and fatty acid synthesis. ...Substantial suppression of eosinophilic airway inflammation by Dex coincided with a specifi …
Dex markedly reduced Af-induced eosinophilic airway inflammation, which was coupled with an overall reduction in lung glycolysis, glu …
Dexamethasone inhibits the proliferation of tumor cells.
Wu Y, Xia R, Dai C, Yan S, Xie T, Liu B, Gan L, Zhuang Z, Huang Q. Wu Y, et al. Cancer Manag Res. 2019 Feb 1;11:1141-1154. doi: 10.2147/CMAR.S187659. eCollection 2019. Cancer Manag Res. 2019. PMID: 30774442 Free PMC article.
OBJECTIVE: Dexamethasone (DEX) is a glucocorticoid that is commonly used in clinics. Previously, DEX has been shown to inhibit the function of immune system; however, DEX is often used to treat side reactions, such as nausea and vomiting caused by chemotherap …
OBJECTIVE: Dexamethasone (DEX) is a glucocorticoid that is commonly used in clinics. Previously, DEX has been shown to inhibit …
Fabrication and evaluation of a BMP-2/dexamethasone co-loaded gelatin sponge scaffold for rapid bone regeneration.
Gan Q, Pan H, Zhang W, Yuan Y, Qian J, Liu C. Gan Q, et al. Regen Biomater. 2022 Feb 16;9:rbac008. doi: 10.1093/rb/rbac008. eCollection 2022. Regen Biomater. 2022. PMID: 35592142 Free PMC article.
We also investigate the mechanism of osteogenesis induced by BMP-2 and Dex with C2C12, a multipotent muscle-derived progenitor cell. The results show that the gelatin scaffold with Dex and BMP-2 can significantly accelerate osteogenesis in vivo. It is indicated that …
We also investigate the mechanism of osteogenesis induced by BMP-2 and Dex with C2C12, a multipotent muscle-derived progenitor cell. …
Total tanshinones protect against acute lung injury through the PLCγ2/NLRP3 inflammasome signaling pathway.
Li X, Qiu H, Gan J, Liu Z, Yang S, Yuan R, Gao H. Li X, et al. J Ethnopharmacol. 2023 Oct 5;314:116478. doi: 10.1016/j.jep.2023.116478. Epub 2023 Apr 28. J Ethnopharmacol. 2023. PMID: 37121449
The experiment was randomly divided into six groups: control, LPS, LPS + si-NC, LPA + si-Nek7, LPS + TTN, and DEX. Pathological alterations were explored by H&E staining. The expression levels of proteins related to the NLRP3 inflammasome were analyzed by Western blott …
The experiment was randomly divided into six groups: control, LPS, LPS + si-NC, LPA + si-Nek7, LPS + TTN, and DEX. Pathological alter …
Dexmedetomidine Reduces Perioperative Opioid Consumption and Postoperative Pain Intensity in Neurosurgery: A Meta-analysis.
Liu Y, Liang F, Liu X, Shao X, Jiang N, Gan X. Liu Y, et al. J Neurosurg Anesthesiol. 2018 Apr;30(2):146-155. doi: 10.1097/ANA.0000000000000403. J Neurosurg Anesthesiol. 2018. PMID: 28079737 Review.
BACKGROUND: Dexmedetomidine (DEX) has been administered to patients during neurosurgery. Some studies have found that DEX could reduce perioperative opioid consumption and postoperative pain intensity. ...The purpose of this meta-analysis was to assess the efficacy …
BACKGROUND: Dexmedetomidine (DEX) has been administered to patients during neurosurgery. Some studies have found that DEX coul …
Blockade of cyclophilin D rescues dexamethasone-induced oxidative stress in gingival tissue.
He Y, Zhang L, Zhu Z, Xiao A, Yu H, Gan X. He Y, et al. PLoS One. 2017 Mar 8;12(3):e0173270. doi: 10.1371/journal.pone.0173270. eCollection 2017. PLoS One. 2017. PMID: 28273124 Free PMC article.
We demonstrated that the expression level of CypD significantly increased under Dex treatment. Blockade of CypD by pharmaceutical inhibitor cyclosporine A (CsA) significantly protected against Dex-induced oxidative stress accumulation in gingival tissue. ...We also …
We demonstrated that the expression level of CypD significantly increased under Dex treatment. Blockade of CypD by pharmaceutical inh …
FOXO1 involvement in insulin resistance-related pro-inflammatory cytokine production in hepatocytes.
Miao H, Zhang Y, Lu Z, Liu Q, Gan L. Miao H, et al. Inflamm Res. 2012 Apr;61(4):349-58. doi: 10.1007/s00011-011-0417-3. Epub 2012 Jan 6. Inflamm Res. 2012. PMID: 22223069
METHODS: We determined FOXO1 expression and activity, insulin and NF-kappaB signaling, and pro-inflammatory cytokine production in tumor necrosis factor-alpha (TNF-alpha)- or dexamethasone (DEX)-induced IR model in vitro and in high fat diet-induced obese or diabetic db/db …
METHODS: We determined FOXO1 expression and activity, insulin and NF-kappaB signaling, and pro-inflammatory cytokine production in tumor nec …
Monitored anesthesia care with dexmedetomidine: a prospective, randomized, double-blind, multicenter trial.
Candiotti KA, Bergese SD, Bokesch PM, Feldman MA, Wisemandle W, Bekker AY; MAC Study Group. Candiotti KA, et al. Anesth Analg. 2010 Jan 1;110(1):47-56. doi: 10.1213/ane.0b013e3181ae0856. Epub 2009 Aug 27. Anesth Analg. 2010. PMID: 19713256 Clinical Trial.
METHODS: Three hundred twenty-six patients were randomized 2:2:1 to DEX 0.5 microg/kg, DEX 1 microg/kg, or saline placebo initial loading dose, followed by a maintenance infusion of 0.2-1.0 microg x kg(-1) x h(-1) of DEX (or equivalent volume of saline) titra …
METHODS: Three hundred twenty-six patients were randomized 2:2:1 to DEX 0.5 microg/kg, DEX 1 microg/kg, or saline placebo init …
Perioperative application of dexmedetomidine for postoperative systemic inflammatory response syndrome in patients undergoing percutaneous nephrolithotomy lithotripsy: results of a randomised controlled trial.
Deng Y, Tan F, Gan X, Li X, Ge M, Gong C, Hei Z, Zhu Q, Zhou S. Deng Y, et al. BMJ Open. 2018 Nov 3;8(11):e019008. doi: 10.1136/bmjopen-2017-019008. BMJ Open. 2018. PMID: 30391912 Free PMC article. Clinical Trial.
PARTICIPANTS: A total of 190 patients were randomly assigned to receive Dex (DEX group, n=95) or saline control (CON group, n=95) and completed the study. In the DEX group, Dex was loaded (1 g/kg) before anaesthesia induction and was infused (0.5 g/kg/ …
PARTICIPANTS: A total of 190 patients were randomly assigned to receive Dex (DEX group, n=95) or saline control (CON group, n= …
E-selectin-targeted copolymer reduces atherosclerotic lesions, adverse cardiac remodeling, and dysfunction.
Tsoref O, Tyomkin D, Amit U, Landa N, Cohen-Rosenboim O, Kain D, Golan M, Naftali-Shani N, David A, Leor J. Tsoref O, et al. J Control Release. 2018 Oct 28;288:136-147. doi: 10.1016/j.jconrel.2018.08.029. Epub 2018 Aug 27. J Control Release. 2018. PMID: 30165141
To target E-selectin on activated endothelium, we developed a new N-(2-hydroxypropyl)methacrylamide (HPMA)-based E-selectin binding copolymer with or without dexamethasone (Dex) (designated P-(Esbp)-Dex and P-Esbp, respectively). To determine the effect of P-(Esbp)- …
To target E-selectin on activated endothelium, we developed a new N-(2-hydroxypropyl)methacrylamide (HPMA)-based E-selectin binding copolyme …
37 results