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Page 1
Showing results for denis binding
Search for Denis Bindiug instead (1 results)
[Apalutamide, Erleada®].
Sautois B, Denis C. Sautois B, et al. Rev Med Liege. 2022 Oct;77(10):609-615. Rev Med Liege. 2022. PMID: 36226398 Free article. French.
10 months. Apalutamide is a nonsteroidal antiandrogen agent that binds directly to the ligand-binding domain of the androgen receptor without agonist activity. ...
10 months. Apalutamide is a nonsteroidal antiandrogen agent that binds directly to the ligand-binding domain of the androgen r …
Hot-Spots of Mcl-1 Protein.
Denis C, Sopková-de Oliveira Santos J, Bureau R, Voisin-Chiret AS. Denis C, et al. J Med Chem. 2020 Feb 13;63(3):928-943. doi: 10.1021/acs.jmedchem.9b00983. Epub 2019 Oct 16. J Med Chem. 2020. PMID: 31580668 Review.
Analysis of structural data highlights the high importance of the P2/P3 pockets for the binding of nonpeptide ligands. In order to guide medicinal chemists into making more selective and potent Mcl-1 inhibitors, the Mcl-1 protein is compared to other antiapoptotic proteins …
Analysis of structural data highlights the high importance of the P2/P3 pockets for the binding of nonpeptide ligands. In order to gu …
Lipids and retroviruses.
Raulin J. Raulin J. Lipids. 2000 Feb;35(2):123-30. doi: 10.1007/BF02664760. Lipids. 2000. PMID: 10757541 Review.
The role that lipids may play in enveloped viruses is reviewed. Small lipid molecules can influence retrovirus binding to cell receptors, plasma membrane fusion, and transcription. ...
The role that lipids may play in enveloped viruses is reviewed. Small lipid molecules can influence retrovirus binding to cell recept …
von Willebrand factor and inflammation.
Kawecki C, Lenting PJ, Denis CV. Kawecki C, et al. J Thromb Haemost. 2017 Jul;15(7):1285-1294. doi: 10.1111/jth.13696. J Thromb Haemost. 2017. PMID: 28671350 Free article. Review.
Finally, a more direct link between VWF and inflammation has become apparent with the discovery that VWF is able to recruit leukocytes, either via direct leukocyte binding or by recruiting platelets which in turn will attract leukocytes. ...
Finally, a more direct link between VWF and inflammation has become apparent with the discovery that VWF is able to recruit leukocytes, eith …
Antennal Morphology and Localization of a Pheromone-Binding Protein of Lobesia botrana (Denis & Schiffermuller) (Lepidoptera: Tortricidae).
Godoy R, Aburto C, Lizana P, Venthur H, Palma-Millanao R, Méndez L, Panichini M, Moraga F, Bardehle L, Quiroz A, Mutis A. Godoy R, et al. Neotrop Entomol. 2019 Jun;48(3):422-432. doi: 10.1007/s13744-018-0648-x. Epub 2018 Nov 9. Neotrop Entomol. 2019. PMID: 30414018
Therefore, we used light microscopy and scanning electron microscopy to investigate the morphology and distribution of sensilla in the antennae of Lobesia botrana (Denis & Schiffermuller). In addition, we studied the expression of the gene encoding for pheromone-bin …
Therefore, we used light microscopy and scanning electron microscopy to investigate the morphology and distribution of sensilla in the anten …
Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
Carivenc C, Maveyraud L, Blanger C, Ballereau S, Roy-Camille C, Nguyen MC, Génisson Y, Guilhot C, Chalut C, Pedelacq JD, Mourey L. Carivenc C, et al. Sci Rep. 2021 Sep 10;11(1):18042. doi: 10.1038/s41598-021-97197-4. Sci Rep. 2021. PMID: 34508141 Free PMC article.
Finally, in crystallo screening of potent inhibitors from the National Cancer Institute library identified a hydroxypyrimidinethione derivative that binds PptAb. Both compounds could serve as scaffolds for the future development of phosphopantetheinyl transferases inhibito …
Finally, in crystallo screening of potent inhibitors from the National Cancer Institute library identified a hydroxypyrimidinethione derivat …
Microtubule's conformational cap.
Chrétien D, Jáinosi I, Taveau JC, Flyvbjerg H. Chrétien D, et al. Cell Struct Funct. 1999 Oct;24(5):299-303. doi: 10.1247/csf.24.299. Cell Struct Funct. 1999. PMID: 15216886 Free article.
Uncovering uncharacterized binding of transcription factors from ATAC-seq footprinting data.
Schultheis H, Bentsen M, Heger V, Looso M. Schultheis H, et al. Sci Rep. 2024 Apr 23;14(1):9275. doi: 10.1038/s41598-024-59989-2. Sci Rep. 2024. PMID: 38654130 Free PMC article.
However, while over 1600 TFs have been described in the human genome, only ~ 700 of these have a known binding motif. Thus, a substantial number of FPs without overlap to a known DNA motif are normally discarded from FP analysis. ...DENIS includes functionality (1) …
However, while over 1600 TFs have been described in the human genome, only ~ 700 of these have a known binding motif. Thus, a substan …
Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin.
Zhang H, Modenutti C, Nekkanti YPK, Denis M, Bermejo IA, Lefèbre J, Che K, Kim D, Kagelmacher M, Kurzbach D, Nazaré M, Rademacher C. Zhang H, et al. ACS Chem Biol. 2022 Oct 21;17(10):2728-2733. doi: 10.1021/acschembio.2c00626. Epub 2022 Sep 26. ACS Chem Biol. 2022. PMID: 36153965 Free PMC article.
Prompted by the observation that its human homologue exhibits different binding specificities for these small molecules, we report here our investigations to define their exact binding site. ...Taking solvent paramagnetic relaxation enhancement NMR studies together …
Prompted by the observation that its human homologue exhibits different binding specificities for these small molecules, we report he …
940 results