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A Xenotransplant Model of Human Brain Tumors in Wild-Type Mice.
Hoffmann N, Fernández V, Pereira RC, Rancati S, Pelizzoli R, De Pietri Tonelli D. Hoffmann N, et al. iScience. 2020 Jan 24;23(1):100813. doi: 10.1016/j.isci.2019.100813. Epub 2019 Dec 30. iScience. 2020. PMID: 31931429 Free PMC article.
Here, we exploit the "immune-privileged" developmental time window to achieve orthotopic xenotransplantation of human brain tumor cells in wild-type (WT) mice. We find that, when transplanted in utero, human glioblastoma (GBM) cells readily integrate in the embryonic mouse …
Here, we exploit the "immune-privileged" developmental time window to achieve orthotopic xenotransplantation of human brain tumor cells in w …
The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.
Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN. Gupta S, et al. PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278022 Free PMC article. Clinical Trial.