Effects of two dietary fibers as part of ready-to-eat cereal (RTEC) breakfasts on perceived appetite and gut hormones in overweight women

Nutrients. 2015 Feb 13;7(2):1245-66. doi: 10.3390/nu7021245.

Abstract

The effects of an enzyme-hydrolyzed arabinoxylan from wheat (AXOS) versus an intact arabinoxylan from flax (FLAX) added to a ready-to-eat cereal (RTEC) on the postprandial appetitive, hormonal, and metabolic responses in overweight women (BMI 25.0-29.9 kg/m2) were evaluated. Subsequent meal energy intake was also assessed. Two randomized, double-blind, crossover design studies were completed. For trial 1, the participants consumed the following RTEC breakfast, matched for total weight and varied in energy content: low-fiber (LF, 4 g); high-fiber (HF, 15 g) as either AXOS or FLAX. For trial 2, the participants consumed LF, HF-AXOS, and HF-FLAX RTECs but also consumed another LF breakfast that was isocaloric (LF-iso) to that of the HF breakfasts. Perceived appetite and blood samples (trial 2 only) were assessed before and after breakfast. An ad libitum lunch was offered 4 h post-breakfast. No differences in postprandial appetite responses were observed among any breakfasts in either trial. The HF-AXOS and HF-FLAX led to increased postprandial GLP-1 and peptide YY (PYY) concentrations vs. LF-iso. No differences were observed in lunch meal energy intake among breakfast meals in either trial. Collectively, these data suggest that 15 g of low molecular weight fiber added to RTECs did not affect perceived appetite or subsequent energy intake despite differences in satiety hormone signaling in overweight females.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Appetite*
  • Body Mass Index
  • Breakfast*
  • Case-Control Studies
  • Cross-Over Studies
  • Dietary Fiber / administration & dosage
  • Dietary Fiber / pharmacology*
  • Double-Blind Method
  • Edible Grain* / classification
  • Energy Intake
  • Female
  • Flax / chemistry
  • Gastrointestinal Hormones / blood*
  • Glucagon-Like Peptide 1 / blood
  • Humans
  • Overweight / diet therapy*
  • Peptide YY / blood
  • Postprandial Period
  • Satiation
  • Triticum / chemistry
  • Young Adult

Substances

  • Dietary Fiber
  • Gastrointestinal Hormones
  • Peptide YY
  • Glucagon-Like Peptide 1