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Safety and efficacy of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer.
Gynecol Oncol. 2023 Mar;170:241-247. doi: 10.1016/j.ygyno.2023.01.020. Epub 2023 Feb 1.
Gynecol Oncol. 2023.
PMID: 36736157
Free article.
The paradigm shift in anaphylaxis management cannot occur without changing minds.
La Mantia A, Stukus DR.
La Mantia A, et al.
Ann Allergy Asthma Immunol. 2024 Apr;132(4):419-420. doi: 10.1016/j.anai.2024.01.008.
Ann Allergy Asthma Immunol. 2024.
PMID: 38569755
No abstract available.
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Phase 1b study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate, in combination with carboplatin and bevacizumab in patients with platinum-sensitive ovarian cancer.
Richardson DL, Moore KN, Vergote I, Gilbert L, Martin LP, Mantia-Smaldone GM, Castro CM, Provencher D, Matulonis UA, Stec J, Wang Y, Method M, O'Malley DM.
Richardson DL, et al.
Gynecol Oncol. 2024 Mar 5;185:186-193. doi: 10.1016/j.ygyno.2024.01.045. Online ahead of print.
Gynecol Oncol. 2024.
PMID: 38447347
Free article.
The median DOR was 10.9 months; median PFS was 13.5 months. AEs (any grade) occurred as expected, based on each agent's safety profile; most common were diarrhea (83%), nausea (76%), fatigue (73%), thrombocytopenia (71%), and blurred vision (68%). ...
The median DOR was 10.9 months; median PFS was 13.5 months. AEs (any grade) occurred as expected, based on each agent's safety profil …
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