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Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection.
Smith-Peter E, Séguin DL, St-Pierre É, Sekulovic O, Jeanneau S, Tremblay-Tétreault C, Lamontagne AM, Jacques PÉ, Lafontaine DA, Fortier LC. Smith-Peter E, et al. Among authors: seguin dl. RNA Biol. 2021 Nov 12;18(sup2):699-710. doi: 10.1080/15476286.2021.1978768. Epub 2021 Oct 6. RNA Biol. 2021. PMID: 34612173 Free PMC article.
Comparative Pharmacodynamics of Single-Dose Oritavancin and Daily High-Dose Daptomycin Regimens against Vancomycin-Resistant Enterococcus faecium Isolates in an In Vitro Pharmacokinetic/Pharmacodynamic Model of Infection.
Belley A, Lalonde-Séguin D, Arhin FF, Moeck G. Belley A, et al. Among authors: lalonde seguin d. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e01265-17. doi: 10.1128/AAC.01265-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28784674 Free PMC article.