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Page 1
Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease.
Karvelis T, Druteika G, Bigelyte G, Budre K, Zedaveinyte R, Silanskas A, Kazlauskas D, Venclovas Č, Siksnys V. Karvelis T, et al. Among authors: kazlauskas d. Nature. 2021 Nov;599(7886):692-696. doi: 10.1038/s41586-021-04058-1. Epub 2021 Oct 7. Nature. 2021. PMID: 34619744 Free PMC article.
TnpB structure reveals minimal functional core of Cas12 nuclease family.
Sasnauskas G, Tamulaitiene G, Druteika G, Carabias A, Silanskas A, Kazlauskas D, Venclovas Č, Montoya G, Karvelis T, Siksnys V. Sasnauskas G, et al. Among authors: kazlauskas d. Nature. 2023 Apr;616(7956):384-389. doi: 10.1038/s41586-023-05826-x. Epub 2023 Apr 5. Nature. 2023. PMID: 37020015
Expansion of the global RNA virome reveals diverse clades of bacteriophages.
Neri U, Wolf YI, Roux S, Camargo AP, Lee B, Kazlauskas D, Chen IM, Ivanova N, Zeigler Allen L, Paez-Espino D, Bryant DA, Bhaya D; RNA Virus Discovery Consortium; Krupovic M, Dolja VV, Kyrpides NC, Koonin EV, Gophna U. Neri U, et al. Among authors: kazlauskas d. Cell. 2022 Oct 13;185(21):4023-4037.e18. doi: 10.1016/j.cell.2022.08.023. Epub 2022 Sep 28. Cell. 2022. PMID: 36174579 Free article.
Diversity and evolution of B-family DNA polymerases.
Kazlauskas D, Krupovic M, Guglielmini J, Forterre P, Venclovas Č. Kazlauskas D, et al. Nucleic Acids Res. 2020 Oct 9;48(18):10142-10156. doi: 10.1093/nar/gkaa760. Nucleic Acids Res. 2020. PMID: 32976577 Free PMC article. Review.
Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing.
Bigelyte G, Duchovska B, Zedaveinyte R, Sasnauskas G, Sinkunas T, Dalgediene I, Tamulaitiene G, Silanskas A, Kazlauskas D, Valančauskas L, Madariaga-Marcos J, Seidel R, Siksnys V, Karvelis T. Bigelyte G, et al. Among authors: kazlauskas d. Nucleic Acids Res. 2024 Apr 12;52(6):3234-3248. doi: 10.1093/nar/gkae016. Nucleic Acids Res. 2024. PMID: 38261981 Free PMC article.
A catalogue of biochemically diverse CRISPR-Cas9 orthologs.
Gasiunas G, Young JK, Karvelis T, Kazlauskas D, Urbaitis T, Jasnauskaite M, Grusyte MM, Paulraj S, Wang PH, Hou Z, Dooley SK, Cigan M, Alarcon C, Chilcoat ND, Bigelyte G, Curcuru JL, Mabuchi M, Sun Z, Fuchs RT, Schildkraut E, Weigele PR, Jack WE, Robb GB, Venclovas Č, Siksnys V. Gasiunas G, et al. Among authors: kazlauskas d. Nat Commun. 2020 Nov 2;11(1):5512. doi: 10.1038/s41467-020-19344-1. Nat Commun. 2020. PMID: 33139742 Free PMC article.
Origins and Evolution of the Global RNA Virome.
Wolf YI, Kazlauskas D, Iranzo J, Lucía-Sanz A, Kuhn JH, Krupovic M, Dolja VV, Koonin EV. Wolf YI, et al. Among authors: kazlauskas d. mBio. 2018 Nov 27;9(6):e02329-18. doi: 10.1128/mBio.02329-18. mBio. 2018. PMID: 30482837 Free PMC article.
24 results