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The funny current in genetically modified mice.
DiFrancesco ML, Mesirca P, Bidaud I, Isbrandt D, Mangoni ME. DiFrancesco ML, et al. Prog Biophys Mol Biol. 2021 Nov;166:39-50. doi: 10.1016/j.pbiomolbio.2021.06.003. Epub 2021 Jun 12. Prog Biophys Mol Biol. 2021. PMID: 34129872 Review.
In addition, gene targeting of f-(HCN) channel isoforms have contributed to elucidating the current's role in the regulation of heart rate by the parasympathetic nervous system. This review is dedicated to Dario DiFrancesco on his retirement....
In addition, gene targeting of f-(HCN) channel isoforms have contributed to elucidating the current's role in the regulation of heart rate b …
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease.
Boyett MR, Yanni J, Tellez J, Bucchi A, Mesirca P, Cai X, Logantha SJRJ, Wilson C, Anderson C, Ariyaratnam J, Stuart L, Nakao S, Abd Allah E, Jones S, Lancaster M, Stephenson R, Chandler N, Smith M, Bussey C, Monfredi O, Morris G, Billeter R, Mangoni ME, Zhang H, Hart G, D'Souza A. Boyett MR, et al. Prog Biophys Mol Biol. 2021 Nov;166:61-85. doi: 10.1016/j.pbiomolbio.2021.06.008. Epub 2021 Jun 28. Prog Biophys Mol Biol. 2021. PMID: 34197836 Free article. Review.
The funny current, I(f), was first recorded in the heart 40 or more years ago by Dario DiFrancesco and others. Since then, we have learnt that I(f) plays an important role in pacemaking in the sinus node, the innate pacemaker of the heart, and more recently evidence has ac …
The funny current, I(f), was first recorded in the heart 40 or more years ago by Dario DiFrancesco and others. Since then, we have le …