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Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance.
Naso F, Intartaglia D, Falanga D, Soldati C, Polishchuk E, Giamundo G, Tiberi P, Marrocco E, Scudieri P, Di Malta C, Trapani I, Nusco E, Salierno FG, Surace EM, Galietta LJ, Banfi S, Auricchio A, Ballabio A, Medina DL, Conte I. Naso F, et al. Among authors: falanga d. EMBO J. 2020 Apr 15;39(8):e102468. doi: 10.15252/embj.2019102468. Epub 2020 Mar 10. EMBO J. 2020. PMID: 32154600 Free PMC article.
MiR-211 is essential for adult cone photoreceptor maintenance and visual function.
Barbato S, Marrocco E, Intartaglia D, Pizzo M, Asteriti S, Naso F, Falanga D, Bhat RS, Meola N, Carissimo A, Karali M, Prosser HM, Cangiano L, Surace EM, Banfi S, Conte I. Barbato S, et al. Among authors: falanga d. Sci Rep. 2017 Dec 5;7(1):17004. doi: 10.1038/s41598-017-17331-z. Sci Rep. 2017. PMID: 29209045 Free PMC article.