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Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on Leishmania amazonensis.
de Santiago-Silva KM, Bortoleti BTDS, Oliveira LDN, Maia FLA, Castro JC, Costa IC, Lazarin DB, Wardell JL, Wardell SMSV, Albuquerque MG, Lima CHDS, Pavanelli WR, Bispo MLF, Gonçalves RSB. de Santiago-Silva KM, et al. Among authors: lazarin db. Antibiotics (Basel). 2022 Oct 13;11(10):1402. doi: 10.3390/antibiotics11101402. Antibiotics (Basel). 2022. PMID: 36290060 Free PMC article.
Solidagenone acts on promastigotes of L. amazonensis by inducing apoptosis-like processes on intracellular amastigotes by IL-12p70/ROS/NO pathway activation.
Bortoleti BTDS, Gonçalves MD, Tomiotto-Pellissier F, Contato VM, Silva TF, de Matos RLN, Detoni MB, Rodrigues ACJ, Carloto AC, Lazarin DB, Arakawa NS, Costa IN, Conchon-Costa I, Miranda-Sapla MM, Wowk PF, Pavanelli WR. Bortoleti BTDS, et al. Among authors: lazarin db. Phytomedicine. 2021 May;85:153536. doi: 10.1016/j.phymed.2021.153536. Epub 2021 Mar 3. Phytomedicine. 2021. PMID: 33765552