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IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
Mucciolo G, Curcio C, Roux C, Li WY, Capello M, Curto R, Chiarle R, Giordano D, Satolli MA, Lawlor R, Scarpa A, Lukac P, Stakheev D, Provero P, Vannucci L, Mak TW, Novelli F, Cappello P. Mucciolo G, et al. Among authors: giordano d. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2020395118. doi: 10.1073/pnas.2020395118. Proc Natl Acad Sci U S A. 2021. PMID: 33526692 Free PMC article.
In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination.
Mandili G, Curcio C, Bulfamante S, Follia L, Ferrero G, Mazza E, Principe M, Cordero F, Satolli MA, Spadi R, Evangelista A, Giordano D, Viet D, Cappello P, Novelli F. Mandili G, et al. Among authors: giordano d. J Immunother Cancer. 2020 Oct;8(2):e001071. doi: 10.1136/jitc-2020-001071. J Immunother Cancer. 2020. PMID: 33115943 Free PMC article.
Immune-Complexome Analysis Identifies Immunoglobulin-Bound Biomarkers That Predict the Response to Chemotherapy of Pancreatic Cancer Patients.
Mandili G, Follia L, Ferrero G, Katayama H, Hong W, Momin AA, Capello M, Giordano D, Spadi R, Satolli MA, Evangelista A, Hanash SM, Cordero F, Novelli F. Mandili G, et al. Among authors: giordano d. Cancers (Basel). 2020 Mar 21;12(3):746. doi: 10.3390/cancers12030746. Cancers (Basel). 2020. PMID: 32245227 Free PMC article.
Circulating autoantibodies to alpha-enolase (ENO1) and far upstream element-binding protein 1 (FUBP1) are negative prognostic factors for pancreatic cancer patient survival.
Curcio C, Rosso T, Brugiapaglia S, Guadagnin G, Giordano D, Castellino B, Satolli MA, Spadi R, Campra D, Moro F, Papotti MG, Bertero L, Cassoni P, De Angelis C, Langella S, Ferrero A, Armentano S, Bellotti G, Fenocchio E, Nuzzo A, Ciccone G, Novelli F. Curcio C, et al. Among authors: giordano d. Clin Exp Med. 2023 Dec;23(8):5089-5100. doi: 10.1007/s10238-023-01236-5. Epub 2023 Nov 1. Clin Exp Med. 2023. PMID: 37910256 Free PMC article.
Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.
Niccolai E, Taddei A, Ricci F, Rolla S, D'Elios MM, Benagiano M, Bechi P, Bencini L, Ringressi MN, Pini A, Castiglione F, Giordano D, Satolli MA, Coratti A, Cianchi F, Bani D, Prisco D, Novelli F, Amedei A. Niccolai E, et al. Among authors: giordano d. Clin Sci (Lond). 2016 Feb;130(4):247-58. doi: 10.1042/CS20150437. Epub 2015 Nov 20. Clin Sci (Lond). 2016. PMID: 26590104