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Multifunctional PLGA nanoparticles combining transferrin-targetability and pH-stimuli sensitivity enhanced doxorubicin intracellular delivery and in vitro antineoplastic activity in MDR tumor cells.
Toxicol In Vitro. 2021 Sep;75:105192. doi: 10.1016/j.tiv.2021.105192. Epub 2021 May 11.
Toxicol In Vitro. 2021.
PMID: 33984456
Free article.
Overcoming MDR by Associating Doxorubicin and pH-Sensitive PLGA Nanoparticles Containing a Novel Organoselenium Compound-An In Vitro Study.
Macedo LB, Nogueira-Librelotto DR, Mathes D, de Vargas JM, da Rosa RM, Rodrigues OED, Vinardell MP, Mitjans M, Rolim CMB.
Macedo LB, et al. Among authors: mathes d.
Pharmaceutics. 2021 Dec 29;14(1):80. doi: 10.3390/pharmaceutics14010080.
Pharmaceutics. 2021.
PMID: 35056975
Free PMC article.
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Transferrin-Decorated PLGA Nanoparticles Loaded with an Organoselenium Compound as an Innovative Approach to Sensitize MDR Tumor Cells: An In Vitro Study Using 2D and 3D Cell Models.
Macedo LB, Nogueira-Librelotto DR, Mathes D, Pieta TB, Mainardi Pillat M, Rosa RMD, Rodrigues OED, Vinardell MP, Rolim CMB.
Macedo LB, et al. Among authors: mathes d.
Nanomaterials (Basel). 2023 Aug 11;13(16):2306. doi: 10.3390/nano13162306.
Nanomaterials (Basel). 2023.
PMID: 37630891
Free PMC article.
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Co-Delivery of an Innovative Organoselenium Compound and Paclitaxel by pH-Responsive PCL Nanoparticles to Synergistically Overcome Multidrug Resistance in Cancer.
Mathes D, Macedo LB, Pieta TB, Maia BC, Rodrigues OED, Leal JG, Wendt M, Rolim CMB, Mitjans M, Nogueira-Librelotto DR.
Mathes D, et al.
Pharmaceutics. 2024 Apr 26;16(5):590. doi: 10.3390/pharmaceutics16050590.
Pharmaceutics. 2024.
PMID: 38794252
Free PMC article.
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