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Year Number of Results
2012 1
2013 2
2014 1
2015 1
2017 2
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2019 1
2020 1
2021 4
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2023 3
2024 3

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19 results

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Page 1
CDK-independent role of D-type cyclins in regulating DNA mismatch repair.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M. Rona G, et al. Among authors: laverty dj. Mol Cell. 2024 Apr 4;84(7):1224-1242.e13. doi: 10.1016/j.molcel.2024.02.010. Epub 2024 Mar 7. Mol Cell. 2024. PMID: 38458201 Free article.
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization.
Chen J, Laverty DJ, Talele S, Bale A, Carlson BL, Porath KA, Bakken KK, Burgenske DM, Decker PA, Vaubel RA, Eckel-Passow JE, Bhargava R, Lou Z, Hamerlik P, Harley B, Elmquist WF, Nagel ZD, Gupta SK, Sarkaria JN. Chen J, et al. Among authors: laverty dj. Sci Transl Med. 2024 Feb 14;16(734):eadj5962. doi: 10.1126/scitranslmed.adj5962. Epub 2024 Feb 14. Sci Transl Med. 2024. PMID: 38354228
D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M. Rona G, et al. Among authors: laverty dj. bioRxiv [Preprint]. 2024 Jan 13:2024.01.12.575420. doi: 10.1101/2024.01.12.575420. bioRxiv. 2024. PMID: 38260436 Free PMC article. Preprint.
Selective Inhibition of DNA Polymerase β by a Covalent Inhibitor.
Yuhas SC, Laverty DJ, Lee H, Majumdar A, Greenberg MM. Yuhas SC, et al. Among authors: laverty dj. J Am Chem Soc. 2021 Jun 2;143(21):8099-8107. doi: 10.1021/jacs.1c02453. Epub 2021 May 20. J Am Chem Soc. 2021. PMID: 34014094 Free PMC article.
Differential immunomodulatory effect of PARP inhibition in BRCA1 deficient and competent tumor cells.
Alvarado-Cruz I, Mahmoud M, Khan M, Zhao S, Oeck S, Meas R, Clairmont K, Quintana V, Zhu Y, Porciuncula A, Wyatt H, Ma S, Shyr Y, Kong Y, LoRusso PM, Laverty D, Nagel ZD, Schalper KA, Krauthammer M, Sweasy JB. Alvarado-Cruz I, et al. Among authors: laverty d. Biochem Pharmacol. 2021 Feb;184:114359. doi: 10.1016/j.bcp.2020.114359. Epub 2020 Dec 4. Biochem Pharmacol. 2021. PMID: 33285109 Free PMC article.
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation.
Nguyen MT, Moiani D, Ahmed Z, Arvai AS, Namjoshi S, Shin DS, Fedorov Y, Selvik EJ, Jones DE, Pink J, Yan Y, Laverty DJ, Nagel ZD, Tainer JA, Gerson SL. Nguyen MT, et al. Among authors: laverty dj. Prog Biophys Mol Biol. 2021 Aug;163:143-159. doi: 10.1016/j.pbiomolbio.2021.02.004. Epub 2021 Mar 3. Prog Biophys Mol Biol. 2021. PMID: 33675849 Free PMC article.
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death.
Houl JH, Ye Z, Brosey CA, Balapiti-Modarage LPF, Namjoshi S, Bacolla A, Laverty D, Walker BL, Pourfarjam Y, Warden LS, Babu Chinnam N, Moiani D, Stegeman RA, Chen MK, Hung MC, Nagel ZD, Ellenberger T, Kim IK, Jones DE, Ahmed Z, Tainer JA. Houl JH, et al. Among authors: laverty d. Nat Commun. 2019 Dec 11;10(1):5654. doi: 10.1038/s41467-019-13508-4. Nat Commun. 2019. PMID: 31827085 Free PMC article.
19 results