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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1950 1
1951 1
1953 4
1954 1
1955 1
1956 1
1957 4
1958 2
1959 5
1960 4
1961 12
1962 15
1963 16
1964 30
1965 26
1966 50
1967 51
1968 70
1969 103
1970 108
1971 134
1972 307
1973 363
1974 400
1975 669
1976 698
1977 641
1978 678
1979 749
1980 889
1981 963
1982 1109
1983 1365
1984 1696
1985 1875
1986 2061
1987 2223
1988 2561
1989 2870
1990 3129
1991 3645
1992 4108
1993 4822
1994 4953
1995 5218
1996 5438
1997 5463
1998 5621
1999 5644
2000 5992
2001 6433
2002 6270
2003 6604
2004 7463
2005 7769
2006 8019
2007 8337
2008 8532
2009 9037
2010 9631
2011 10299
2012 11098
2013 11267
2014 11473
2015 11347
2016 10805
2017 10269
2018 10171
2019 10559
2020 10548
2021 10680
2022 9400
2023 8684
2024 3905
2025 1

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272,808 results

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Page 1
Showing results for dna single
Search for Dana Lingle instead (1 results)
Single-molecule manipulation quantification of site-specific DNA binding.
Zhao X, Guo S, Lu C, Chen J, Le S, Fu H, Yan J. Zhao X, et al. Curr Opin Chem Biol. 2019 Dec;53:106-117. doi: 10.1016/j.cbpa.2019.08.006. Epub 2019 Oct 31. Curr Opin Chem Biol. 2019. PMID: 31677535 Review.
The execution of functions on DNA relies on complex interactions between DNA and proteins in a sequence and structure dependent manner. Accurate quantification of the affinity and kinetics of these interactions is critical for understanding the molecular mechanisms …
The execution of functions on DNA relies on complex interactions between DNA and proteins in a sequence and structure dependen …
Shining a Spotlight on DNA: Single-Molecule Methods to Visualise DNA.
Kaur G, Lewis JS, van Oijen AM. Kaur G, et al. Molecules. 2019 Jan 30;24(3):491. doi: 10.3390/molecules24030491. Molecules. 2019. PMID: 30704053 Free PMC article. Review.
The ability to watch single molecules of DNA has revolutionised how we study biological transactions concerning nucleic acids. ...This review focuses on summarising some of the methodological developments made to visualise individual DNA molecules and discuss …
The ability to watch single molecules of DNA has revolutionised how we study biological transactions concerning nucleic acids. …
Molecular scaffolds: when DNA becomes the hardware for single-molecule investigations.
Gosse C, Strick TR, Kostrz D. Gosse C, et al. Curr Opin Chem Biol. 2019 Dec;53:192-203. doi: 10.1016/j.cbpa.2019.09.006. Epub 2019 Nov 20. Curr Opin Chem Biol. 2019. PMID: 31759266 Review.
Over the past few decades, single-molecule manipulation has been widely applied to the real-time analysis of biomolecular interactions. ...More specifically, we present molecular scaffolds as an emerging concept and describe their use in single-molecule force spectr …
Over the past few decades, single-molecule manipulation has been widely applied to the real-time analysis of biomolecular interaction …
Influence of DNA Lesions on Polymerase-Mediated DNA Replication at Single-Molecule Resolution.
Gahlon HL, Romano LJ, Rueda D. Gahlon HL, et al. Chem Res Toxicol. 2017 Nov 20;30(11):1972-1983. doi: 10.1021/acs.chemrestox.7b00224. Epub 2017 Oct 23. Chem Res Toxicol. 2017. PMID: 29020440 Free article. Review.
These techniques have also been used to gain a deeper understanding of how single DNA polymerases behave at the site of the damage in a DNA substrate. In this review, we evaluate single-molecule studies that have examined the interaction between DNA …
These techniques have also been used to gain a deeper understanding of how single DNA polymerases behave at the site of the da …
Current and Emerging Methods for the Synthesis of Single-Stranded DNA.
Hao M, Qiao J, Qi H. Hao M, et al. Genes (Basel). 2020 Jan 21;11(2):116. doi: 10.3390/genes11020116. Genes (Basel). 2020. PMID: 31973021 Free PMC article. Review.
Methods for synthesizing arbitrary single-strand DNA (ssDNA) fragments are rapidly becoming fundamental tools for gene editing, DNA origami, DNA storage, and other applications. ...
Methods for synthesizing arbitrary single-strand DNA (ssDNA) fragments are rapidly becoming fundamental tools for gene editing …
Single DNA molecule analysis: applications of molecular combing.
Lebofsky R, Bensimon A. Lebofsky R, et al. Brief Funct Genomic Proteomic. 2003 Jan;1(4):385-96. doi: 10.1093/bfgp/1.4.385. Brief Funct Genomic Proteomic. 2003. PMID: 15239885 Review.
To understand these changes and how they vary from cell to cell, single DNA molecules from both normal and abnormal cell populations must be examined and compared. ...Single-molecule DNA replication can also be monitored through fluorescent detection o …
To understand these changes and how they vary from cell to cell, single DNA molecules from both normal and abnormal cell popul …
Recent advances in Forensic DNA Phenotyping of appearance, ancestry and age.
Kayser M, Branicki W, Parson W, Phillips C. Kayser M, et al. Forensic Sci Int Genet. 2023 Jul;65:102870. doi: 10.1016/j.fsigen.2023.102870. Epub 2023 Apr 6. Forensic Sci Int Genet. 2023. PMID: 37084623 Free article. Review.
Forensic DNA Phenotyping (FDP) comprises the prediction of a person's externally visible characteristics regarding appearance, biogeographic ancestry and age from DNA of crime scene samples, to provide investigative leads to help find unknown perpetrators tha …
Forensic DNA Phenotyping (FDP) comprises the prediction of a person's externally visible characteristics regarding appearance, …
Visualizing protein-DNA interactions at the single-molecule level.
Hilario J, Kowalczykowski SC. Hilario J, et al. Curr Opin Chem Biol. 2010 Feb;14(1):15-22. doi: 10.1016/j.cbpa.2009.10.035. Epub 2009 Nov 27. Curr Opin Chem Biol. 2010. PMID: 19945909 Free PMC article. Review.
Recent advancements in single-molecule methods have allowed researchers to directly observe proteins acting on their DNA targets in real-time. ...These single-molecule studies have provided new insights into nearly all aspects of DNA metabolism. ...
Recent advancements in single-molecule methods have allowed researchers to directly observe proteins acting on their DNA targe …
Amplification-refractory mutation system (ARMS) analysis of point mutations.
Little S. Little S. Curr Protoc Hum Genet. 2001 May;Chapter 9:Unit 9.8. doi: 10.1002/0471142905.hg0908s07. Curr Protoc Hum Genet. 2001. PMID: 18428319
The amplification-refractory mutation system (ARMS) is a simple method for detecting any mutation involving single base changes or small deletions. ARMS is based on the use of sequence-specific PCR primers that allow amplification of test DNA only when the target al …
The amplification-refractory mutation system (ARMS) is a simple method for detecting any mutation involving single base changes or sm …
272,808 results
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