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Showing results for dana freshly
Search for Dana Freshley instead (1 results)
Single-cell analysis of localized prostate cancer patients links high Gleason score with an immunosuppressive profile.
Adorno Febles VR, Hao Y, Ahsan A, Wu J, Qian Y, Zhong H, Loeb S, Makarov DV, Lepor H, Wysock J, Taneja SS, Huang WC, Becker DJ, Balar AV, Melamed J, Deng FM, Ren Q, Kufe D, Wong KK, Adeegbe DO, Deng J, Wise DR. Adorno Febles VR, et al. Prostate. 2023 Jun;83(9):840-849. doi: 10.1002/pros.24524. Epub 2023 Mar 29. Prostate. 2023. PMID: 36988342
METHODS: Through single-cell RNA sequencing and multicolor flow cytometry of freshly isolated prostatectomy specimens and matched peripheral blood, we aimed to characterize the tumor immune microenvironment (TME) of localized prostate cancer (PCa), including HGPCa and low- …
METHODS: Through single-cell RNA sequencing and multicolor flow cytometry of freshly isolated prostatectomy specimens and matched per …
Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma.
Panovska D, Nazari P, Cole B, Creemers PJ, Derweduwe M, Solie L, Van Gassen S, Claeys A, Verbeke T, Cohen EF, Tolstorukov MY, Saeys Y, Van der Planken D, Bosisio FM, Put E, Bamps S, Clement PM, Verfaillie M, Sciot R, Ligon KL, De Vleeschouwer S, Antoranz A, De Smet F. Panovska D, et al. Cell Mol Life Sci. 2023 May 12;80(6):147. doi: 10.1007/s00018-023-04772-1. Cell Mol Life Sci. 2023. PMID: 37171617
BACKGROUND: Functional profiling of freshly isolated glioblastoma (GBM) cells is being evaluated as a next-generation method for precision oncology. ...CONCLUSION: PROSPERO provides a precise way to evaluate therapy efficacy by measuring molecular drug responses using spec …
BACKGROUND: Functional profiling of freshly isolated glioblastoma (GBM) cells is being evaluated as a next-generation method for prec …
Isolation of Human Neutrophils from Whole Blood and Buffy Coats.
Hsu AY, Peng Z, Luo H, Loison F. Hsu AY, et al. J Vis Exp. 2021 Sep 17;(175). doi: 10.3791/62837. J Vis Exp. 2021. PMID: 34605812
There, neutrophils perform an array of functions to kill invading pathogens and mediate immune signaling. Freshly purified neutrophils from human blood are the model of choice for study, as no cell line fully replicates PMN functions and biology. ...
There, neutrophils perform an array of functions to kill invading pathogens and mediate immune signaling. Freshly purified neutrophil …
Antimutagenesis and anticarcinogenesis, from the past to the future.
Weisburger JH. Weisburger JH. Mutat Res. 2001 Sep 1;480-481:23-35. doi: 10.1016/s0027-5107(01)00166-x. Mutat Res. 2001. PMID: 11506796 Review.
With the realization that there are carcinogens that in a metabolically activated attack DNA, in contrast to other agents that act by promoting, enhancing processes through totally distinct mechanisms, it became possible to develop and apply tests for DNA reactivity, in a prokary …
With the realization that there are carcinogens that in a metabolically activated attack DNA, in contrast to other agents that act by promot …
Development and characterization of a hydrogel-based adhesive patch for sealing open-globe injuries.
Jumelle C, Yung A, Sani ES, Taketani Y, Gantin F, Bourel L, Wang S, Yüksel E, Seneca S, Annabi N, Dana R. Jumelle C, et al. Acta Biomater. 2022 Jan 1;137:53-63. doi: 10.1016/j.actbio.2021.10.021. Epub 2021 Oct 19. Acta Biomater. 2022. PMID: 34673229 Free PMC article.
Our in vitro studies showed no sign of cytotoxicity of the hydrogels. Moreover, the hydrogel patches showed higher adhesion on freshly explanted pig eyeballs compared to a marketed ocular sealant. ...
Our in vitro studies showed no sign of cytotoxicity of the hydrogels. Moreover, the hydrogel patches showed higher adhesion on freshly
Novel therapies targeting the myeloma cell and its bone marrow microenvironment.
Hideshima T, Chauhan D, Podar K, Schlossman RL, Richardson P, Anderson KC. Hideshima T, et al. Semin Oncol. 2001 Dec;28(6):607-12. doi: 10.1016/s0093-7754(01)90033-8. Semin Oncol. 2001. PMID: 11740818 Review.
The proteasome inhibitor PS-341 directly inhibits proliferation and induces apoptosis in both human MM cell lines and freshly isolated patient's MM cells which are resistant to Mel, Dox, and Dex. ...
The proteasome inhibitor PS-341 directly inhibits proliferation and induces apoptosis in both human MM cell lines and freshly isolate …
Daylight-driven carbon exchange through a vertically structured microbial community.
Moran JJ, Bernstein HC, Mobberley JM, Thompson AM, Kim YM, Dana KL, Cory AB, Courtney S, Renslow RS, Fredrickson JK, Kreuzer HW, Lipton MS. Moran JJ, et al. Front Microbiol. 2023 May 26;14:1139213. doi: 10.3389/fmicb.2023.1139213. eCollection 2023. Front Microbiol. 2023. PMID: 37303779 Free PMC article.
Stable isotope proteomic analysis revealed rapid C exchange between cyanobacterial and associated heterotrophic community members during the day with decreased exchange at night. We observed strong diel control on the spatial exchange of freshly fixed C within tightly inte …
Stable isotope proteomic analysis revealed rapid C exchange between cyanobacterial and associated heterotrophic community members during the …
Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells.
Myers SA, Rhoads A, Cocco AR, Peckner R, Haber AL, Schweitzer LD, Krug K, Mani DR, Clauser KR, Rozenblatt-Rosen O, Hacohen N, Regev A, Carr SA. Myers SA, et al. Mol Cell Proteomics. 2019 May;18(5):995-1009. doi: 10.1074/mcp.RA118.001259. Epub 2019 Feb 21. Mol Cell Proteomics. 2019. PMID: 30792265 Free PMC article.
Utilizing a combination of facile cell collection from cell sorting, solid-state isobaric labeling and multiplexing of peptides, and small-scale fractionation, we profiled the proteomes of 12 freshly isolated, primary murine immune cell types. Analyzing half of the 3e5 cel …
Utilizing a combination of facile cell collection from cell sorting, solid-state isobaric labeling and multiplexing of peptides, and small-s …
Gamma-irradiation reduces the allogenicity of donor corneas.
Stevenson W, Cheng SF, Emami-Naeini P, Hua J, Paschalis EI, Dana R, Saban DR. Stevenson W, et al. Invest Ophthalmol Vis Sci. 2012 Oct 1;53(11):7151-8. doi: 10.1167/iovs.12-9609. Invest Ophthalmol Vis Sci. 2012. PMID: 22991417 Free PMC article.
Orthotopic penetrating keratoplasty was performed using irradiated or nonirradiated (freshly excised) C57BL/6 donor grafts and BALB/c or C57BL/6 recipients. ...
Orthotopic penetrating keratoplasty was performed using irradiated or nonirradiated (freshly excised) C57BL/6 donor grafts and BALB/c …
Circulating CD2+ monocytes are dendritic cells.
Crawford K, Gabuzda D, Pantazopoulos V, Xu J, Clement C, Reinherz E, Alper CA. Crawford K, et al. J Immunol. 1999 Dec 1;163(11):5920-8. J Immunol. 1999. PMID: 10570278
FACS analysis of CD2+ and CD2- monocytes revealed no significant difference in the expression of adhesion molecules (CD11a/b/c), class II Ags (HLA-DR, -DQ, -DP), myeloid Ags (CD13, CD14, CD33), or costimulatory molecules (CD80, CD86). Freshly isolated CD2+ and CD2- monocyt …
FACS analysis of CD2+ and CD2- monocytes revealed no significant difference in the expression of adhesion molecules (CD11a/b/c), class II Ag …
69 results