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The complex nature of fragile site plasticity and its importance in cancer.
Curr Opin Cell Biol. 2016 Jun;40:131-136. doi: 10.1016/j.ceb.2016.03.017. Epub 2016 Apr 7.
Curr Opin Cell Biol. 2016.
PMID: 27062332
Review.
Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability.
Sarni D, Barroso S, Shtrikman A, Irony-Tur Sinai M, Oren YS, Aguilera A, Kerem B.
Sarni D, et al.
Cell Rep. 2022 Sep 27;40(13):111397. doi: 10.1016/j.celrep.2022.111397.
Cell Rep. 2022.
PMID: 36170822
Free PMC article.
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3D genome organization contributes to genome instability at fragile sites.
Sarni D, Sasaki T, Irony Tur-Sinai M, Miron K, Rivera-Mulia JC, Magnuson B, Ljungman M, Gilbert DM, Kerem B.
Sarni D, et al.
Nat Commun. 2020 Jul 17;11(1):3613. doi: 10.1038/s41467-020-17448-2.
Nat Commun. 2020.
PMID: 32680994
Free PMC article.
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Nucleotide deficiency promotes genomic instability in early stages of cancer development.
Bester AC, Roniger M, Oren YS, Im MM, Sarni D, Chaoat M, Bensimon A, Zamir G, Shewach DS, Kerem B.
Bester AC, et al. Among authors: sarni d.
Cell. 2011 Apr 29;145(3):435-46. doi: 10.1016/j.cell.2011.03.044.
Cell. 2011.
PMID: 21529715
Free PMC article.
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