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Translational control of human acetyl-CoA carboxylase 1 mRNA is mediated by an internal ribosome entry site in response to ER stress, serum deprivation or hypoxia mimetic CoCl2.
Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):388-398. doi: 10.1016/j.bbalip.2018.01.006. Epub 2018 Jan 16.
Biochim Biophys Acta Mol Cell Biol Lipids. 2018.
PMID: 29343429
hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress.
Damiano F, Rochira A, Tocci R, Alemanno S, Gnoni A, Siculella L.
Damiano F, et al.
Biochem J. 2013 Jan 15;449(2):543-53. doi: 10.1042/BJ20120906.
Biochem J. 2013.
PMID: 23106379
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Lipid accumulation stimulates the cap-independent translation of SREBP-1a mRNA by promoting hnRNP A1 binding to its 5'-UTR in a cellular model of hepatic steatosis.
Siculella L, Tocci R, Rochira A, Testini M, Gnoni A, Damiano F.
Siculella L, et al.
Biochim Biophys Acta. 2016 May;1861(5):471-81. doi: 10.1016/j.bbalip.2016.02.003. Epub 2016 Feb 8.
Biochim Biophys Acta. 2016.
PMID: 26869449
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Expression of citrate carrier gene is activated by ER stress effectors XBP1 and ATF6α, binding to an UPRE in its promoter.
Damiano F, Tocci R, Gnoni GV, Siculella L.
Damiano F, et al.
Biochim Biophys Acta. 2015 Jan;1849(1):23-31. doi: 10.1016/j.bbagrm.2014.10.004. Epub 2014 Oct 27.
Biochim Biophys Acta. 2015.
PMID: 25450523
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