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Showing results for along cong
Search for Dalong Cong instead (2 results)
MRE11 UFMylation promotes ATM activation.
Wang Z, Gong Y, Peng B, Shi R, Fan D, Zhao H, Zhu M, Zhang H, Lou Z, Zhou J, Zhu WG, Cong YS, Xu X. Wang Z, et al. Nucleic Acids Res. 2019 May 7;47(8):4124-4135. doi: 10.1093/nar/gkz110. Nucleic Acids Res. 2019. PMID: 30783677 Free PMC article.
DNA double-strand breaks (DSBs) are the most toxic DNA lesion and their repair is orchestrated by the ATM kinase. ATM is activated via the MRE11-RAD50-NBS1 (MRN) complex along with its autophosphorylation at S1981 and acetylation at K3106. ...
DNA double-strand breaks (DSBs) are the most toxic DNA lesion and their repair is orchestrated by the ATM kinase. ATM is activated via the M …
The methyl-CpG-binding domain 2 facilitates pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation.
Wang Y, Zhang L, Huang T, Wu GR, Zhou Q, Wang FX, Chen LM, Sun F, Lv Y, Xiong F, Zhang S, Yu Q, Yang P, Gu W, Xu Y, Zhao J, Zhang H, Xiong W, Wang CY. Wang Y, et al. Eur Respir J. 2022 Sep 29;60(3):2003697. doi: 10.1183/13993003.03697-2020. Print 2022 Sep. Eur Respir J. 2022. PMID: 35086828 Free PMC article.
Herein, we demonstrate that lungs originated from IPF patients and mice after bleomycin (BLM)-induced pulmonary fibrosis are characterised by altered DNA methylation along with overexpression in myofibroblasts of methyl-CpG-binding domain 2 (MBD2), a reader responsible for …
Herein, we demonstrate that lungs originated from IPF patients and mice after bleomycin (BLM)-induced pulmonary fibrosis are characterised b …
Integrative multi-omics deciphers the spatial characteristics of host-gut microbiota interactions in Crohn's disease.
Gao X, Sun R, Jiao N, Liang X, Li G, Gao H, Wu X, Yang M, Chen C, Sun X, Chen L, Wu W, Cong Y, Zhu R, Guo T, Liu Z. Gao X, et al. Cell Rep Med. 2023 Jun 20;4(6):101050. doi: 10.1016/j.xcrm.2023.101050. Epub 2023 May 11. Cell Rep Med. 2023. PMID: 37172588 Free PMC article.
We observe aberrant antimicrobial immunity and metabolic processes across multi-tissues during CD and determine bacterial transmission along with altered microbial communities and ecological patterns. ...
We observe aberrant antimicrobial immunity and metabolic processes across multi-tissues during CD and determine bacterial transmission al …
The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression.
Tang J, Wang S, Weng M, Guo Q, Ren L, He Y, Cui Z, Cong M, Qin M, Yu J, Su R, Li X. Tang J, et al. Cancer Res. 2023 Nov 1;83(21):3593-3610. doi: 10.1158/0008-5472.CAN-23-0557. Cancer Res. 2023. PMID: 37560971
In this study, we identified increased translational efficiency (TE) as a hallmark of colorectal cancer by evaluating the transcriptomic and proteomic features of patients with colorectal cancer, along with comparative transcriptomic and ribosome-protected mRNA analysis in …
In this study, we identified increased translational efficiency (TE) as a hallmark of colorectal cancer by evaluating the transcriptomic and …
Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway.
Niu C, Chen Z, Kim KT, Sun J, Xue M, Chen G, Li S, Shen Y, Zhu Z, Wang X, Liang J, Jiang C, Cong W, Jin L, Li X. Niu C, et al. Autophagy. 2019 May;15(5):843-870. doi: 10.1080/15548627.2019.1569913. Epub 2019 Jan 27. Autophagy. 2019. PMID: 30653446 Free PMC article.
We observed an obvious inhibition of hyperglycemia-triggered autophagosome synthesis in both the diabetic retinal vasculature and cultured HUVECs by metformin, along with restoration of hyperglycemia-impaired Hedgehog (Hh) pathway activity. ...
We observed an obvious inhibition of hyperglycemia-triggered autophagosome synthesis in both the diabetic retinal vasculature and cultured H …
Sirt3 deficiency accelerates ovarian senescence without affecting spermatogenesis in aging mice.
Zhu J, Yang Q, Li H, Wang Y, Jiang Y, Wang H, Cong L, Xu J, Shen Z, Chen W, Zeng X, Wang M, Lei M, Sun Y. Zhu J, et al. Free Radic Biol Med. 2022 Nov 20;193(Pt 2):511-525. doi: 10.1016/j.freeradbiomed.2022.10.324. Epub 2022 Nov 3. Free Radic Biol Med. 2022. PMID: 36336229
Meanwhile, in ovaries of Sirt3 null mice, the impaired mitochondrial functions were shown by decreases in mitochondrial respiratory complexes, along with lower levels of mitochondrial fusion (OPA1, MFN2) and fission (DRP1, FIS1) proteins. er levels of mitochondrial fusion …
Meanwhile, in ovaries of Sirt3 null mice, the impaired mitochondrial functions were shown by decreases in mitochondrial respiratory complexe …
The applied principles of EEG analysis methods in neuroscience and clinical neurology.
Zhang H, Zhou QQ, Chen H, Hu XQ, Li WG, Bai Y, Han JX, Wang Y, Liang ZH, Chen D, Cong FY, Yan JQ, Li XL. Zhang H, et al. Mil Med Res. 2023 Dec 19;10(1):67. doi: 10.1186/s40779-023-00502-7. Mil Med Res. 2023. PMID: 38115158 Free PMC article. Review.
Second, five main directions for the methods of EEG analysis, including power spectrum analysis, time-frequency analysis, connectivity analysis, source localization methods, and machine learning methods, are described in the main section, along with different sub-methods a …
Second, five main directions for the methods of EEG analysis, including power spectrum analysis, time-frequency analysis, connectivity analy …
Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT.
Han W, Jin M, Liu C, Zhao Q, Wang S, Wang Y, Yin Y, Peng C, Wang Y, Cong Y. Han W, et al. Sci Adv. 2023 Mar 17;9(11):eade1207. doi: 10.1126/sciadv.ade1207. Epub 2023 Mar 15. Sci Adv. 2023. PMID: 36921056 Free PMC article.
Through cryo-electron microscopy analysis, we present a more complete picture of TRiC-assisted tubulin/actin folding along TRiC adenosine triphosphatase cycle, under the coordination of co-chaperone plp2. ...
Through cryo-electron microscopy analysis, we present a more complete picture of TRiC-assisted tubulin/actin folding along TRiC adeno …
A multi-responsive healable supercapacitor.
Qin H, Liu P, Chen C, Cong HP, Yu SH. Qin H, et al. Nat Commun. 2021 Jul 14;12(1):4297. doi: 10.1038/s41467-021-24568-w. Nat Commun. 2021. PMID: 34262049 Free PMC article.
Notably, the device delivers a highest areal capacitance of 1264 mF cm(-2) among the reported healable supercapacitors and restores ~ 90% of initial capacitances over ten healing cycles. These prominent performance advantages along with the facile device-assembly method ma …
Notably, the device delivers a highest areal capacitance of 1264 mF cm(-2) among the reported healable supercapacitors and restores ~ 90% of …
Getting on the right track: Interactions between viruses and the cytoskeletal motor proteins.
Río-Bergé C, Cong Y, Reggiori F. Río-Bergé C, et al. Traffic. 2023 Mar;24(3):114-130. doi: 10.1111/tra.12835. Epub 2022 Feb 18. Traffic. 2023. PMID: 35146839 Free article. Review.
Motor proteins, which comprise the dynein, kinesin and myosin superfamilies, are a remarkable group of accessory proteins that mainly mediate the intracellular transport of cargoes along with the cytoskeleton. Like other cellular structures and pathways, viruses can exploi …
Motor proteins, which comprise the dynein, kinesin and myosin superfamilies, are a remarkable group of accessory proteins that mainly mediat …
270 results