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Year | Number of Results |
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2013 | 1 |
2021 | 1 |
2022 | 3 |
2023 | 4 |
2024 | 0 |
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Page 1
Advancements in Phosphodiesterase 5 Inhibitors: Unveiling Present and Future Perspectives.
Pharmaceuticals (Basel). 2023 Sep 6;16(9):1266. doi: 10.3390/ph16091266.
Pharmaceuticals (Basel). 2023.
PMID: 37765073
Free PMC article.
Review.
An overview of cdc2-like kinase 1 (Clk1) inhibitors and their therapeutic indications.
ElHady AK, El-Gamil DS, Abadi AH, Abdel-Halim M, Engel M.
ElHady AK, et al. Among authors: el gamil ds.
Med Res Rev. 2023 Mar;43(2):343-398. doi: 10.1002/med.21928. Epub 2022 Oct 19.
Med Res Rev. 2023.
PMID: 36262046
Review.
Item in Clipboard
5-Methoxybenzothiophene-2-Carboxamides as Inhibitors of Clk1/4: Optimization of Selectivity and Cellular Potency.
ElHady AK, El-Gamil DS, Chen PJ, Hwang TL, Abadi AH, Abdel-Halim M, Engel M.
ElHady AK, et al. Among authors: el gamil ds.
Molecules. 2021 Feb 13;26(4):1001. doi: 10.3390/molecules26041001.
Molecules. 2021.
PMID: 33668683
Free PMC article.
Item in Clipboard
Discovery of novel 5-methoxybenzothiophene hydrazides as metabolically stable Clk1 inhibitors with high potency and unprecedented Clk1 isoenzyme selectivity.
El-Gamil DS, ElHady AK, Chen PJ, Hwang TL, Abadi AH, Abdel-Halim M, Engel M.
El-Gamil DS, et al.
Eur J Med Chem. 2023 Feb 5;247:115019. doi: 10.1016/j.ejmech.2022.115019. Epub 2022 Dec 15.
Eur J Med Chem. 2023.
PMID: 36580731
Item in Clipboard
Development of novel conformationally restricted selective Clk1/4 inhibitors through creating an intramolecular hydrogen bond involving an imide linker.
El-Gamil DS, ElHady AK, Chen PJ, Hwang TL, Abadi AH, Abdel-Halim M, Engel M.
El-Gamil DS, et al.
Eur J Med Chem. 2022 Aug 5;238:114411. doi: 10.1016/j.ejmech.2022.114411. Epub 2022 Apr 26.
Eur J Med Chem. 2022.
PMID: 35635953
Item in Clipboard
Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies.
Al-Karmalawy AA, El-Gamil DS, El-Shesheny R, Sharaky M, Alnajjar R, Kutkat O, Moatasim Y, Elagawany M, Al-Rashood ST, Binjubair FA, Eldehna WM, Noreddin AM, Zakaria MY.
Al-Karmalawy AA, et al. Among authors: el gamil ds.
J Enzyme Inhib Med Chem. 2023 Dec;38(1):2202357. doi: 10.1080/14756366.2023.2202357.
J Enzyme Inhib Med Chem. 2023.
PMID: 37092260
Free PMC article.
Item in Clipboard
Design of novel β-carboline derivatives with pendant 5-bromothienyl and their evaluation as phosphodiesterase-5 inhibitors.
El-Gamil DS, Ahmed NS, Gary BD, Piazza GA, Engel M, Hartmann RW, Abadi AH.
El-Gamil DS, et al.
Arch Pharm (Weinheim). 2013 Jan;346(1):23-33. doi: 10.1002/ardp.201200334.
Arch Pharm (Weinheim). 2013.
PMID: 23307609
Free PMC article.
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