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Showing results for daao guo
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Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells.
Alim I, Haskew-Layton RE, Aleyasin H, Guo H, Ratan RR. Alim I, et al. Methods Enzymol. 2014;547:251-73. doi: 10.1016/B978-0-12-801415-8.00014-X. Methods Enzymol. 2014. PMID: 25416362 Free PMC article.
A promising means of regulating endogenous H2O2 is through the expression of peroxide-producing enzyme d-amino acid oxidase (DAAO from Rhodotorula gracilis lacking a peroxisomal targeting sequence). Using viral vectors to express DAAO in distinct cell types and usin …
A promising means of regulating endogenous H2O2 is through the expression of peroxide-producing enzyme d-amino acid oxidase (DAAO fro …
FRBM Mini REVIEW: Chemogenetic approaches to probe redox dysregulation in heart failure.
Guo R, Spyropoulos F, Michel T. Guo R, et al. Free Radic Biol Med. 2024 May 1;217:173-178. doi: 10.1016/j.freeradbiomed.2024.03.027. Epub 2024 Mar 31. Free Radic Biol Med. 2024. PMID: 38565399 Review.
Chemogenetic approaches allow the precise manipulation of cellular signaling to delineate the molecular pathways involved in both physiological and pathological disease states. Approaches utilizing yeast d-amino acid oxidase (DAAO) enable manipulation of intracellular redo …
Chemogenetic approaches allow the precise manipulation of cellular signaling to delineate the molecular pathways involved in both physiologi …
Contributions of spinal D-amino acid oxidase to bone cancer pain.
Huang JL, Chen XL, Guo C, Wang YX. Huang JL, et al. Amino Acids. 2012 Nov;43(5):1905-18. doi: 10.1007/s00726-012-1390-z. Epub 2012 Sep 21. Amino Acids. 2012. PMID: 22996731
Tibia inoculation of carcinoma cells produced mechanical allodynia (but not heat hyperalgesia), in synchronous with induction of DAAO expression and DAAO enzymatic activity, as well as activation of spinal astrocytes marked by GFAP. ...Multi-daily intrathecal inject …
Tibia inoculation of carcinoma cells produced mechanical allodynia (but not heat hyperalgesia), in synchronous with induction of DAAO …
A bi-enzymatic cascade to yield pyruvate as co-substrate for L-tyrosine production.
Guo X, Wu W, Zhang M, Wu L, Huang J. Guo X, et al. Appl Microbiol Biotechnol. 2020 Dec;104(23):10005-10018. doi: 10.1007/s00253-020-10975-4. Epub 2020 Oct 31. Appl Microbiol Biotechnol. 2020. PMID: 33128613
Here, we report a bi-enzymatic cascade involving alanine racemase (ALR) and D-amino acid oxidase (DAAO) to produce pyruvate, as co-substrate for L-tyrosine production, from the cheap substrate L-alanine. The BpALR (ALR from Bacillus pseudofirmus) was used as a whole-cell b …
Here, we report a bi-enzymatic cascade involving alanine racemase (ALR) and D-amino acid oxidase (DAAO) to produce pyruvate, as co-su …
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect?
Ren WH, Guo JD, Cao H, Wang H, Wang PF, Sha H, Ji RR, Zhao ZQ, Zhang YQ. Ren WH, et al. J Neurochem. 2006 Mar;96(6):1636-47. doi: 10.1111/j.1471-4159.2006.03677.x. Epub 2006 Feb 10. J Neurochem. 2006. PMID: 16476080 Free article.
Degradation of endogenous D-serine with DAAO, or selective blockade of the glycine site of NMDA receptors by 7Cl-KYNA, effectively inhibited NMDA-evoked currents in rACC slices. Intra-rACC injection of DAAO (0.1 U) and 7Cl-KYNA (2 and 0.2 mM, 0.6 microL per side) 20 …
Degradation of endogenous D-serine with DAAO, or selective blockade of the glycine site of NMDA receptors by 7Cl-KYNA, effectively in …