Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids.
Senthilkumar P, Dinakaran M, Yogeeswari P, Sriram D, China A, Nagaraja V.
Senthilkumar P, et al.
Eur J Med Chem. 2009 Jan;44(1):345-58. doi: 10.1016/j.ejmech.2008.02.031. Epub 2008 Mar 7.
Eur J Med Chem. 2009.
PMID: 18502542
The compounds were evaluated for antimycobacterial in vitro and in vivo against Mycobacterium tuberculosis H37Rv (MTB), multi-drug resistant Mycobacterium tuberculosis (MDR-TB) and Mycobacterium smegmatis (MC(2)) and also tested for the ability to inhibit the supercoiling activit …
The compounds were evaluated for antimycobacterial in vitro and in vivo against Mycobacterium tuberculosis H37Rv (MTB), multi-drug resistant …