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1975 1
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1980 1
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1984 1
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1989 2
1990 2
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1993 2
1994 5
1995 5
1996 4
1997 3
1998 3
1999 5
2000 7
2001 9
2002 5
2003 7
2004 8
2005 4
2006 7
2007 7
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2024 0

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147 results

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Page 1
Vitamin D and cancer.
Spina CS, Tangpricha V, Uskokovic M, Adorinic L, Maehr H, Holick MF. Spina CS, et al. Anticancer Res. 2006 Jul-Aug;26(4A):2515-24. Anticancer Res. 2006. PMID: 16886659 Free article. Review.
Once activated 1,25-dihydroxyvitamin D [1,25(OH)2D3] functions as a potent inhibitor of normal and cancer cellular proliferation. Vitamin D deficiency in mice led to a 60% increase in colon tumor growth, compared to vitamin D-sufficient mice. ...
Once activated 1,25-dihydroxyvitamin D [1,25(OH)2D3] functions as a potent inhibitor of normal and cancer cellular proliferation. Vit …
Vitamin D: a negative endocrine regulator of the renin-angiotensin system and blood pressure.
Li YC, Qiao G, Uskokovic M, Xiang W, Zheng W, Kong J. Li YC, et al. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):387-92. doi: 10.1016/j.jsbmb.2004.03.004. J Steroid Biochem Mol Biol. 2004. PMID: 15225806 Review.
Clinical and epidemiological studies have suggested a correlation between Vitamin D-deficiency and high blood pressure. Our recent studies demonstrate that Vitamin D is a potent endocrine suppressor of renin biosynthesis to regulate the RAS. ...In normal mice, Vitam …
Clinical and epidemiological studies have suggested a correlation between Vitamin D-deficiency and high blood pressure. Our recent st …
Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.
Adorini L, Penna G, Giarratana N, Uskokovic M. Adorini L, et al. J Cell Biochem. 2003 Feb 1;88(2):227-33. doi: 10.1002/jcb.10340. J Cell Biochem. 2003. PMID: 12520519 Review.
Dendritic cells (DCs) not only induce but also modulate T cell activation. 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] induces DCs with a tolerogenic phenotype, characterized by decreased expression of CD40, CD80, and CD86 costimulatory molecules, low IL-12 and enh …
Dendritic cells (DCs) not only induce but also modulate T cell activation. 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] induce …
Entering the era of nanoscience: time to be so small.
Uskoković V. Uskoković V. J Biomed Nanotechnol. 2013 Sep;9(9):1441-70. doi: 10.1166/jbn.2013.1642. J Biomed Nanotechnol. 2013. PMID: 23980495 Free PMC article. Review.
In part, this perspective article resembles standing on the constantly expanding seashore of the coast of nanoscience and nanoengineering and envisioning the parts of the island where the most significant advances may be expected to occur and where, therefore, most of the attenti …
In part, this perspective article resembles standing on the constantly expanding seashore of the coast of nanoscience and nanoengineering an …
Novel Gemini vitamin D(3) analogs have potent antitumor activity.
Saito T, Okamoto R, Haritunians T, O'Kelly J, Uskokovic M, Maehr H, Marczak S, Jankowski P, Badr R, Koeffler HP. Saito T, et al. J Steroid Biochem Mol Biol. 2008 Nov;112(1-3):151-6. doi: 10.1016/j.jsbmb.2008.09.012. Epub 2008 Sep 30. J Steroid Biochem Mol Biol. 2008. PMID: 18938245 Free PMC article.
The active form of vitamin D(3), 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], modulates proliferation and induces differentiation of many cancer cells. ...Also, morphologically differentiation was more prominent compared to 1,25(OH)(2)D(3). Annexin V …
The active form of vitamin D(3), 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], modulates proliferation and induces diff …
Highly active analogs of 1alpha,25-dihydroxyvitamin D(3) that resist metabolism through C-24 oxidation and C-3 epimerization pathways.
Uskokovic MR, Norman AW, Manchand PS, Studzinski GP, Campbell MJ, Koeffler HP, Takeuchi A, Siu-Caldera ML, Rao DS, Reddy GS. Uskokovic MR, et al. Steroids. 2001 Mar-May;66(3-5):463-71. doi: 10.1016/s0039-128x(00)00226-9. Steroids. 2001. PMID: 11179755 Review.
The secosteroid hormone 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)] is metabolized in its target tissues through modifications of both the side chain and the A-ring. ...Assembly of all these protective structural modifications in single molecules has then …
The secosteroid hormone 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)] is metabolized in its target tissues through mo …
Physiological significance of C-28 hydroxylation in the metabolism of 1alpha,25-dihydroxyvitamin D(2).
Rao DS, Siu-Caldera ML, Uskokovic MR, Horst RL, Reddy GS. Rao DS, et al. Arch Biochem Biophys. 1999 Aug 15;368(2):319-28. doi: 10.1006/abbi.1999.1308. Arch Biochem Biophys. 1999. PMID: 10441383
In our previous study, we indicated for the first time that C-28 hydroxylation plays a significant role in the metabolism of 1alpha, 25-dihydroxyvitamin D(2) [1alpha,25(OH)(2)D(2)] by identifying 1alpha,24(S),25,28-tetrahydroxyvitamin D(2) [1alpha,24(S),25, 2 …
In our previous study, we indicated for the first time that C-28 hydroxylation plays a significant role in the metabolism of 1alpha, 25-dihy …
Selective vitamin D receptor modulators and their effects on colorectal tumor growth.
Spina CS, Ton L, Yao M, Maehr H, Wolfe MM, Uskokovic M, Adorini L, Holick MF. Spina CS, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):757-62. doi: 10.1016/j.jsbmb.2006.12.040. J Steroid Biochem Mol Biol. 2007. PMID: 17368190
The active form of vitamin D, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], is an endocrine hormone whose classic role is the maintenance of calcium homeostasis. ...Thus, DG acts as a selective vitamin D receptor modulator (SVDRM) by enhancing select a …
The active form of vitamin D, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], is an endocrine hormone whose classic role …
Signaling pathways for vitamin D-induced differentiation: implications for therapy of proliferative and neoplastic diseases.
Studzinski GP, McLane JA, Uskoković MR. Studzinski GP, et al. Crit Rev Eukaryot Gene Expr. 1993;3(4):279-312. Crit Rev Eukaryot Gene Expr. 1993. PMID: 8286848 Review.
The physiological form of vitamin D, 1 alpha,25-dihydroxyvitamin D3 (1,25D3) is not only a powerful regulator of calcium homeostasis but also a hormone with important roles in cell growth and differentiation. ...
The physiological form of vitamin D, 1 alpha,25-dihydroxyvitamin D3 (1,25D3) is not only a powerful regulator of calcium homeostasis …
Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis.
McNally P, Coughlan C, Bergsson G, Doyle M, Taggart C, Adorini L, Uskokovic MR, El-Nazir B, Murphy P, Greally P, Greene CM, McElvaney NG. McNally P, et al. J Cyst Fibros. 2011 Dec;10(6):428-34. doi: 10.1016/j.jcf.2011.06.013. Epub 2011 Jul 23. J Cyst Fibros. 2011. PMID: 21784717 Free article.
BACKGROUND: 1,25-Dihydroxycholecalciferol (1,25(OH)(2)D(3)) has been shown to mitigate epithelial inflammatory responses after antigen exposure. ...Treatment with 1,25(OH)(2)D(3) was associated with an increase in hCAP18/LL-37 mRNA and protein levels. ...
BACKGROUND: 1,25-Dihydroxycholecalciferol (1,25(OH)(2)D(3)) has been shown to mitigate epithelial inflammatory responses after antige …
147 results